PMID- 6430688
OWN - NLM
STAT- MEDLINE
DCOM- 19840919
LR  - 20190829
IS  - 0013-7219 (Print)
IS  - 0013-7219 (Linking)
VI  - 31
IP  - 2
DP  - 1984 Apr
TI  - Hormone levels of anterior pituitary gland and serum in Nagase analbuminemia 
      rats.
PG  - 185-93
AB  - The hormone levels in the anterior pituitary gland and serum in Nagase 
      analbuminemia rats (NAR), a mutant strain established from Sprague-Dawley rats 
      with hyperlipidemia, were examined. For the anterior pituitary gland, the 
      prolactin, TSH, GH, LH and FSH contents in male NAR were significantly lower than 
      those of normal rats. In female NAR, prolactin, TSH and LH levels were also lower 
      than those in normal rats, whereas FSH and GH were normal. For the serum, the 
      concentrations of TSH, total T3, total and free T4, estradiol-17 beta and 
      testosterone were examined. The serum testosterone concentration in NAR was lower 
      than that of normal rats. Histochemical examination of the hydroxysteroid 
      dehydrogenase (HSD) activity of testes was made in relation to the serum 
      testosterone level. NAR testes, which are rather small compared with those of 
      normal rats, have lower HSD activity. A higher level of serum TSH was seen in 
      NAR. Total and free T4 concentrations were low in the male NAR only. Estradiol-17 
      beta and T3 concentrations in NAR were unchanged. Changes in serum LH and FSH 
      levels during the estrous cycle in NAR were also studied. Their patterns of 
      change are normal.
FAU - Takahashi, M
AU  - Takahashi M
FAU - Wakabayashi, K
AU  - Wakabayashi K
FAU - Nagase, S
AU  - Nagase S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Endocrinol Jpn
JT  - Endocrinologia japonica
JID - 0376546
RN  - 0 (Gonadotropins, Pituitary)
RN  - 0 (Serum Albumin)
RN  - 0 (Thyroid Hormones)
RN  - 3XMK78S47O (Testosterone)
RN  - 4TI98Z838E (Estradiol)
RN  - 9002-62-4 (Prolactin)
RN  - 9002-67-9 (Luteinizing Hormone)
RN  - 9002-68-0 (Follicle Stimulating Hormone)
RN  - 9002-72-6 (Growth Hormone)
RN  - EC 1.1.- (Hydroxysteroid Dehydrogenases)
SB  - IM
MH  - Age Factors
MH  - Animals
MH  - Estradiol/analysis
MH  - Female
MH  - Follicle Stimulating Hormone/analysis
MH  - Gonadotropins, Pituitary/*analysis
MH  - Growth Hormone/analysis
MH  - Hydroxysteroid Dehydrogenases/analysis
MH  - Luteinizing Hormone/analysis
MH  - Male
MH  - Pituitary Gland, Anterior/*analysis
MH  - Prolactin/analysis
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Rats, Mutant Strains/*metabolism
MH  - Serum Albumin/*deficiency
MH  - Sex Factors
MH  - Testosterone/analysis
MH  - Thyroid Hormones/analysis
EDAT- 1984/04/01 00:00
MHDA- 1984/04/01 00:01
CRDT- 1984/04/01 00:00
PHST- 1984/04/01 00:00 [pubmed]
PHST- 1984/04/01 00:01 [medline]
PHST- 1984/04/01 00:00 [entrez]
AID - 10.1507/endocrj1954.31.185 [doi]
PST - ppublish
SO  - Endocrinol Jpn. 1984 Apr;31(2):185-93. doi: 10.1507/endocrj1954.31.185.