PMID- 6442857
OWN - NLM
STAT- MEDLINE
DCOM- 19850528
LR  - 20051117
IS  - 0004-2803 (Print)
IS  - 0004-2803 (Linking)
VI  - 21
IP  - 3
DP  - 1984 Jul-Sep
TI  - Carbohydrate malabsorption in infants with diarrhea: diagnostic and evolutive 
      aspects.
PG  - 136-42
AB  - Twenty three infants with acute or protracted diarrhea were investigated for 
      carbohydrate (CHO) malabsorption during their normal feeding schedules. All 
      infants were fed a chicken-meat formula which contained rice flour and 
      maltodextrin. End-tidal respiratory H2 concentrations were sequentially evaluated 
      in different clinical settings and compared to fecal pH and reducing substances. 
      Fecal pH below 6.0 and/or breath H2 greater than 25 ppm were considered evidence 
      of CHO malabsorption, as these values disappeared while infants were submitted to 
      a trial of CHO withdrawal per os, reappearing after CHO reintroduction. Values of 
      fecal pH greater than 6.0 most often (84,2%) occurred along with H2 less than 25 
      ppm, thus frequently reflecting a good CHO absorption. pH values below 6.0, 
      however, although reflecting CHO malabsorption, did not predict the presence of 
      significant H2 concentrations in expired air. In 44.4% of the well-nourished or 
      only mildly malnourished infants some evidence of CHO malabsorption was present, 
      whereas this occurred in all severely malnourished infants. This last group of 
      infants had a longer history of diarrhea prior to admission and needed a longer 
      hospitalization. The frequency of H2 values greater than 25 ppm decreased 
      progressively during the clinical evolution, along with an increase in CHO 
      ingestion, findings possibly related to nutritional improvement. The hydrogen 
      breath test and fecal pH allowed the diagnosis of CHO fermentation when applied 
      as in this study, without a conventional CHO overload and without previous 
      fasting. It did, however, not predict clinical intolerance, as signs of CHO 
      malabsorption still occurred in infants whose diarrhea had already subsided.
FAU - Maffei, H V
AU  - Maffei HV
FAU - Daher, S R
AU  - Daher SR
FAU - Moreira, F L
AU  - Moreira FL
LA  - eng
PT  - Journal Article
PL  - Brazil
TA  - Arq Gastroenterol
JT  - Arquivos de gastroenterologia
JID - 15310600R
SB  - IM
MH  - Breath Tests
MH  - *Carbohydrate Metabolism
MH  - Diarrhea, Infantile/diet therapy/etiology/*metabolism
MH  - Feces/analysis
MH  - Food, Formulated
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Infant
MH  - Lactose Tolerance Test
MH  - Malabsorption Syndromes/complications/*diagnosis
MH  - Protein-Energy Malnutrition/complications/metabolism
EDAT- 1984/07/01 00:00
MHDA- 1984/07/01 00:01
CRDT- 1984/07/01 00:00
PHST- 1984/07/01 00:00 [pubmed]
PHST- 1984/07/01 00:01 [medline]
PHST- 1984/07/01 00:00 [entrez]
PST - ppublish
SO  - Arq Gastroenterol. 1984 Jul-Sep;21(3):136-42.