PMID- 6456288
OWN - NLM
STAT- MEDLINE
DCOM- 19811118
LR  - 20211018
IS  - 0165-0327 (Print)
IS  - 0165-0327 (Linking)
VI  - 3
IP  - 3
DP  - 1981 Sep
TI  - Initial 6-month follow-up of patients with major depressive disorder. A 
      preliminary report from the NIMH collaborative study of the psychobiology of 
      depression.
PG  - 205-20
AB  - Results from 121 patients with major depressive disorder followed-up at 6 months 
      with a new comprehensive follow-up schedule, the Longitudinal Interval Follow-Up 
      Evaluation (LIFE) indicate that: (1) Forty percent of patients had not recovered 
      from the index episode 6 months after inclusion; (2) Of those patients who 
      recovered, 19% relapsed into another RDC affective episode by the time of the 
      6-month follow-up, and an additional 24% developed some subsequent affective 
      symptoms by that time; (3) Index episodes were relatively long, with a median 
      duration of 25 weeks from onset to recovery for recovered patients, and 67 weeks 
      from onset to follow-up for nonrecovered patients. (4) Duration of the index 
      episode episode prior to entry is a statistically significant predictor of 
      short-term outcome at 6 months, as increasing durations are associated with lower 
      rates of recovery.
FAU - Shapiro, R W
AU  - Shapiro RW
FAU - Keller, M B
AU  - Keller MB
LA  - eng
GR  - R01 MH025478/MH/NIMH NIH HHS/United States
GR  - U01 MH025478/MH/NIMH NIH HHS/United States
PT  - Journal Article
PL  - Netherlands
TA  - J Affect Disord
JT  - Journal of affective disorders
JID - 7906073
SB  - IM
MH  - Adult
MH  - Depressive Disorder/*rehabilitation
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Recurrence
MH  - Sex Factors
MH  - Time Factors
EDAT- 1981/09/01 00:00
MHDA- 1981/09/01 00:01
CRDT- 1981/09/01 00:00
PHST- 1981/09/01 00:00 [pubmed]
PHST- 1981/09/01 00:01 [medline]
PHST- 1981/09/01 00:00 [entrez]
AID - 0165-0327(81)90023-9 [pii]
AID - 10.1016/0165-0327(81)90023-9 [doi]
PST - ppublish
SO  - J Affect Disord. 1981 Sep;3(3):205-20. doi: 10.1016/0165-0327(81)90023-9.