PMID- 6464130 OWN - NLM STAT- MEDLINE DCOM- 19840914 LR - 20190511 IS - 0035-9203 (Print) IS - 0035-9203 (Linking) VI - 78 IP - 3 DP - 1984 TI - The use of Lassa fever convalescent plasma in Nigeria. PG - 319-24 AB - Lassa fever convalescent plasma (LFCP) has been administered to 27 patients in hospitals at Jos and Vom, Nigeria. Among serologically or virologically confirmed cases of Lassa fever (LF) given plasma on or before the 10th day, all eight survived, as did two of three possible LF cases. Of eight patients given LFCP after the 10th day, five died, as did all three possible LF cases. LFCP was also administered to five patients subsequently shown not to have LF, and to a suspected case contact; all survived without complications of therapy. There were 15 cases of LF during this time who did not receive plasma; 11 survived. Most cases of LF who received plasma and survived showed a rapid response to therapy, in contrast with the gradual recovery in those who did not receive LFCP. FAU - Frame, J D AU - Frame JD FAU - Verbrugge, G P AU - Verbrugge GP FAU - Gill, R G AU - Gill RG FAU - Pinneo, L AU - Pinneo L LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PL - England TA - Trans R Soc Trop Med Hyg JT - Transactions of the Royal Society of Tropical Medicine and Hygiene JID - 7506129 SB - IM MH - Adolescent MH - Adult MH - Child, Preschool MH - Female MH - Humans MH - *Immunization, Passive MH - Lassa Fever/*therapy MH - Male MH - Middle Aged MH - Personnel, Hospital EDAT- 1984/01/01 00:00 MHDA- 1984/01/01 00:01 CRDT- 1984/01/01 00:00 PHST- 1984/01/01 00:00 [pubmed] PHST- 1984/01/01 00:01 [medline] PHST- 1984/01/01 00:00 [entrez] AID - 10.1016/0035-9203(84)90107-x [doi] PST - ppublish SO - Trans R Soc Trop Med Hyg. 1984;78(3):319-24. doi: 10.1016/0035-9203(84)90107-x.