PMID- 648029
OWN - NLM
STAT- MEDLINE
DCOM- 19780715
LR  - 20181113
IS  - 0009-9104 (Print)
IS  - 1365-2249 (Electronic)
IS  - 0009-9104 (Linking)
VI  - 31
IP  - 2
DP  - 1978 Feb
TI  - Complex arming in antibody-dependent cell-mediated cytotoxicity: ultrastructural 
      studies of the interaction between human effector cells armed with aggregated 
      anti-DNP antibody and DNP-coated erythrocytes.
PG  - 197-204
AB  - We have examined, by transmission electron microscopy, mixtures of DNP-coated 
      chicken red blood cells and normal human peripheral blood leucocytes 'armed' with 
      alkali-aggregated anti-dinitrophenyl (DNP) antibody. The combination of these 
      observations with chromium release assays enabled us to identify four types of 
      effector cell interacting with the target erythrocytes, viz. phagocytic and 
      non-phagocytic monocytes, neutrophils and lymphocytes. Comparison of these 
      findings with previous work, using antibody-coated targets, allowed us to 
      conclude that the mechanisms and cell types involved are similar. We also 
      demonstrated the short-lived cytotoxic potential of cells armed in this manner.
FAU - Penfold, P L
AU  - Penfold PL
FAU - Walker, L C
AU  - Walker LC
FAU - Roitt, I M
AU  - Roitt IM
LA  - eng
PT  - Journal Article
PL  - England
TA  - Clin Exp Immunol
JT  - Clinical and experimental immunology
JID - 0057202
RN  - 0 (Antibodies)
RN  - 0 (Dinitrobenzenes)
SB  - IM
MH  - Antibodies
MH  - *Antibody-Dependent Cell Cytotoxicity
MH  - Cell Adhesion
MH  - Dinitrobenzenes/immunology
MH  - Erythrocytes/ultrastructure
MH  - Humans
MH  - Leukocytes/immunology/*ultrastructure
MH  - Microscopy, Electron
PMC - PMC1541223
EDAT- 1978/02/01 00:00
MHDA- 1978/02/01 00:01
PMCR- 1979/02/01
CRDT- 1978/02/01 00:00
PHST- 1978/02/01 00:00 [pubmed]
PHST- 1978/02/01 00:01 [medline]
PHST- 1978/02/01 00:00 [entrez]
PHST- 1979/02/01 00:00 [pmc-release]
PST - ppublish
SO  - Clin Exp Immunol. 1978 Feb;31(2):197-204.