PMID- 6482786
OWN - NLM
STAT- MEDLINE
DCOM- 19841109
LR  - 20210107
IS  - 0025-729X (Print)
IS  - 0025-729X (Linking)
VI  - 141
IP  - SP5
DP  - 1984 Sep 1
TI  - Allergy, allergens and allergen standardization.
PG  - S5-8
AB  - Immediate, type 1 allergic reactions occur following interaction between 
      allergen, immunoglobulin E (IgE), and the mast cell or basophil. Allergen-induced 
      activation of these cells leads to the release of a number of mediators that are 
      responsible for the symptoms observed during an allergic reaction. Recent 
      progress in elucidating the structures, and in developing syntheses for platelet 
      aggregating factor and the leukotrienes, promises to increase our understanding 
      of the immunopharmacology of allergic and inflammatory reactions. The need for 
      the standardization of allergen extracts is emphasized, and current activity in 
      this area is highlighted.
FAU - Baldo, B A
AU  - Baldo BA
FAU - Tovey, E R
AU  - Tovey ER
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Australia
TA  - Med J Aust
JT  - The Medical journal of Australia
JID - 0400714
RN  - 0 (Allergens)
RN  - 0 (Platelet Activating Factor)
RN  - 0 (Prostaglandins)
RN  - 0 (SRS-A)
SB  - IM
MH  - *Allergens/standards
MH  - Animals
MH  - Humans
MH  - Hypersensitivity, Immediate/*immunology
MH  - Mast Cells/immunology/physiology
MH  - Papio
MH  - Platelet Activating Factor/immunology
MH  - Prostaglandins/metabolism
MH  - Rabbits
MH  - SRS-A/metabolism
EDAT- 1984/09/01 00:00
MHDA- 1984/09/01 00:01
CRDT- 1984/09/01 00:00
PHST- 1984/09/01 00:00 [pubmed]
PHST- 1984/09/01 00:01 [medline]
PHST- 1984/09/01 00:00 [entrez]
AID - 10.5694/j.1326-5377.1984.tb133020.x [doi]
PST - ppublish
SO  - Med J Aust. 1984 Sep 1;141(SP5):S5-8. doi: 10.5694/j.1326-5377.1984.tb133020.x.