PMID- 6490211
OWN - NLM
STAT- MEDLINE
DCOM- 19841212
LR  - 20190816
IS  - 0167-5273 (Print)
IS  - 0167-5273 (Linking)
VI  - 6
IP  - 4
DP  - 1984 Oct
TI  - Accuracy of absolute left ventricular volumes and cardiac output determined by 
      radionuclide cardiography.
PG  - 505-25
AB  - We determined left ventricular (LV) volumes and derived variables by gated 
      equilibrium radionuclide imaging at rest and during exercise in 12 patients 
      without valve disease or intracardiac shunts. LV volume was determined as the 
      product of the background-corrected LV count rate and an individual attenuation 
      correction factor divided by the count rate in peripheral blood. Attenuation 
      correction was based on measurement of LV depth within the chest from an initial 
      first pass study in the left lateral view and a linear attenuation coefficient of 
      0.156 cm-1 determined in phantom studies. The average LV depth was 8.0 cm (range 
      6.9-9.1) in agreement with an average depth measured by echocardiography of 8.2 
      cm (6.3-9.4), P much greater than 0.05. The correlation between radionuclide (RC) 
      and simultaneous thermodilution (TD) measurements was for cardiac output (CO): r 
      = 0.95; CO (RC) = 1.00 X CO (TD) + 0.10 1/min with a standard error of the 
      estimate (SEE) of 0.79 1/min; for stroke volume (SV): r = 0.90; SV(RC) = 0.93 X 
      SV (TD) + 5 ml; SEE = 8 ml; for end-diastolic volume (EDV): r = 0.96; EDV(RC) = 
      1.06 X EDV(TD) -14 ml; SEE = 27 ml; and for end-systolic volume (ESV): r = 0.98; 
      ESV(RC) = 1.05 X ESV (TD) -6 ml; SEE = 20 ml. The interobserver variation, 
      expressed as the coefficient of variation, was for cardiac output 6%, for stroke 
      volume 6%, for end-diastolic volume 4%, and for end-systolic volume 5%. This 
      method permits non-invasive determination of LV volume and total LV output per 
      beat based exclusively on data obtained during radionuclide imaging.
FAU - Hoilund-Carlsen, P F
AU  - Hoilund-Carlsen PF
FAU - Marving, J
AU  - Marving J
FAU - Rasmussen, S
AU  - Rasmussen S
FAU - Haunso, S
AU  - Haunso S
FAU - Pedersen, J F
AU  - Pedersen JF
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiac Catheterization
MH  - *Cardiac Output
MH  - Cardiac Volume
MH  - Female
MH  - Heart/*diagnostic imaging/physiopathology
MH  - Heart Diseases/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Radionuclide Imaging
MH  - *Stroke Volume
EDAT- 1984/10/01 00:00
MHDA- 1984/10/01 00:01
CRDT- 1984/10/01 00:00
PHST- 1984/10/01 00:00 [pubmed]
PHST- 1984/10/01 00:01 [medline]
PHST- 1984/10/01 00:00 [entrez]
AID - 0167-5273(84)90331-0 [pii]
AID - 10.1016/0167-5273(84)90331-0 [doi]
PST - ppublish
SO  - Int J Cardiol. 1984 Oct;6(4):505-25. doi: 10.1016/0167-5273(84)90331-0.