PMID- 6493016
OWN - NLM
STAT- MEDLINE
DCOM- 19841212
LR  - 20081121
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 16
IP  - 4
DP  - 1984 Aug
TI  - Haptoglobin and serum enzymatic response to maximal exercise in relation to 
      physical fitness.
PG  - 366-70
AB  - This study investigated the potential value of specific cellular responses to 
      acute and chronic exercise as indices of physical fitness. Muscle enzymatic and 
      hemolytic responses following a progressive cycle-ergometer test to maximal 
      aerobic capacity were studied in 12 women and 12 men, aged 27 to 55 yr, who had 
      been previously assigned to "high" and "low" fitness groups. Venous blood samples 
      were obtained at rest prior to the cycle test, immediately following maximal 
      effort, and 1, 2, 4, 6 and 24 h post exercise. The samples were analyzed for 
      hematocrit (Hct), hemoglobin (Hb), lactate dehydrogenase (LDH), serum glutamic 
      oxalacetic transaminase (SGOT), creatine phosphokinase (CK), CK isoenzymes, and 
      haptoglobin (Hapt). Hemoglobin and Hct were the only variables to rise 
      significantly (P less than 0.05) following exercise, and at all sampling times 
      were significantly lower in the women compared with the men; CK was constituted 
      in the MM isoenzyme band at all times; and Hapt levels were significantly lower 
      in high-fitness men and women as compared with low-fitness men and women. These 
      results indicate that one progressive test to maximal aerobic capacity is not 
      sufficient to induce significant muscle enzymatic or hemolytic stress responses. 
      They do suggest, however, that a chronic hemolytic condition exists as a result 
      of aerobic conditioning activity.
FAU - Spitler, D L
AU  - Spitler DL
FAU - Alexander, W C
AU  - Alexander WC
FAU - Hoffler, G W
AU  - Hoffler GW
FAU - Doerr, D F
AU  - Doerr DF
FAU - Buchanan, P
AU  - Buchanan P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Haptoglobins)
RN  - 0 (Hemoglobins)
RN  - 0 (Isoenzymes)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.6.1.1 (Aspartate Aminotransferases)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Adult
MH  - Aspartate Aminotransferases/blood
MH  - Creatine Kinase/blood
MH  - Female
MH  - Haptoglobins/*metabolism
MH  - Hematocrit
MH  - Hemoglobins/metabolism
MH  - Humans
MH  - Isoenzymes
MH  - L-Lactate Dehydrogenase/blood
MH  - Male
MH  - Middle Aged
MH  - *Physical Exertion
MH  - *Physical Fitness
EDAT- 1984/08/01 00:00
MHDA- 1984/08/01 00:01
CRDT- 1984/08/01 00:00
PHST- 1984/08/01 00:00 [pubmed]
PHST- 1984/08/01 00:01 [medline]
PHST- 1984/08/01 00:00 [entrez]
PST - ppublish
SO  - Med Sci Sports Exerc. 1984 Aug;16(4):366-70.