PMID- 6503361
OWN - NLM
STAT- MEDLINE
DCOM- 19850116
LR  - 20190516
IS  - 0025-6196 (Print)
IS  - 0025-6196 (Linking)
VI  - 59
IP  - 12
DP  - 1984 Dec
TI  - Bone mineral density and skeletal fractures in familial benign hypercalcemia 
      (hypocalciuric hypercalcemia).
PG  - 811-5
AB  - To determine whether familial benign hypercalcemia, or familial hypocalciuric 
      hypercalcemia (FHH), has adverse effects on the skeleton, we measured bone 
      mineral density (BMD) in 31 affected persons from 14 families (16 women and 15 
      men), ranging in age from 19 to 68 years. Forearm BMD was measured by 
      single-photon absorptiometry, and spinal BMD was measured by dual-photon 
      absorptiometry. In addition, we systematically queried 82 hypercalcemic and 52 
      normocalcemic family members about skeletal fractures. Both men and women with 
      FHH had normal BMD (expressed as grams per square centimeter) in the lumbar 
      spine, distal radius, and midradius. Osteoporotic-type fractures (vertebrae, hip, 
      and distal radius) were virtually absent in both affected and unaffected family 
      members. Detailed evaluation of larger numbers of of older affected persons may 
      be necessary to resolve this issue definitively, but we conclude provisionally 
      that FHH has no important adverse effects on skeletal health.
FAU - Law, W M Jr
AU  - Law WM Jr
FAU - Wahner, H W
AU  - Wahner HW
FAU - Heath, H 3rd
AU  - Heath H 3rd
LA  - eng
PT  - Journal Article
PL  - England
TA  - Mayo Clin Proc
JT  - Mayo Clinic proceedings
JID - 0405543
RN  - 0 (Minerals)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bone and Bones/*analysis
MH  - Densitometry
MH  - Female
MH  - Fractures, Bone/*etiology
MH  - Humans
MH  - Hypercalcemia/complications/*genetics
MH  - Lumbar Vertebrae/analysis
MH  - Male
MH  - Middle Aged
MH  - Minerals/*analysis
MH  - Radius/analysis
MH  - Risk
OID - NASA: 85059564
EDAT- 1984/12/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1984/12/01 00:00
PHST- 1984/12/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1984/12/01 00:00 [entrez]
AID - S0025-6196(12)65614-6 [pii]
AID - 10.1016/s0025-6196(12)65614-6 [doi]
PST - ppublish
SO  - Mayo Clin Proc. 1984 Dec;59(12):811-5. doi: 10.1016/s0025-6196(12)65614-6.