PMID- 6530755
OWN - NLM
STAT- MEDLINE
DCOM- 19850523
LR  - 20190825
IS  - 0021-4868 (Print)
IS  - 0021-4868 (Linking)
VI  - 25
IP  - 6
DP  - 1984 Nov
TI  - Measurement of lung density in congestive heart failure by computed tomography.
PG  - 979-92
AB  - The computed tomography (CT) number within the region of interest (ROI) was used 
      as a parameter to assess lung density in patients with congestive heart failure. 
      Thirty-eight patients with valvular heart disease (VHD) and 34 patients with 
      ischemic heart disease (IHD) were studied. Based on the New York Heart 
      Association (NYHA) classification, 24 VHD patients were in class I or II (VHD 
      I-II) and the other 14 were in NYHA class III or IV (VHD III-IV). Eighteen 
      patients with IHD were in NYHA class I or II (IHD I-II) and 16 were in class III 
      or IV (IHD III-IV). The CT number was measured bilaterally at the upper, middle 
      and lower levels of the chest and compared with the corresponding values in 21 
      normal subjects (Group N). In a preliminary study on Group N, the CT numbers were 
      insensitive to the size of the ROI, but were closely related to its location. In 
      clinical applications, the mean values of the CT numbers in all six lung fields 
      increased in the order of IHD I-II, to VHD I-II, IHD III-IV and VHD III-IV. 
      Except for patients in IHD I-II, they were significantly larger than in Group N. 
      The relationship between the CT number and the systolic and mean pulmonary 
      arterial pressures and the pulmonary capillary wedge pressure were evaluated in 
      36 patients. Significant correlations were obtained in all six lung fields (r = 
      0.65-0.78, p less than 0.001). The results suggest that measurement of lung 
      density by CT is useful for the quantitative evaluation of the severity of 
      disease in patients with congestive heart failure.
FAU - Nomura, M
AU  - Nomura M
FAU - Miyagi, Y
AU  - Miyagi Y
FAU - Tachi, K
AU  - Tachi K
FAU - Sakabe, Y
AU  - Sakabe Y
FAU - Sakai, Y
AU  - Sakai Y
FAU - Hishida, H
AU  - Hishida H
FAU - Mizuno, Y
AU  - Mizuno Y
FAU - Sasaki, F
AU  - Sasaki F
FAU - Koga, S
AU  - Koga S
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Jpn Heart J
JT  - Japanese heart journal
JID - 0401175
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Pressure
MH  - Coronary Disease/diagnostic imaging
MH  - Female
MH  - Heart Failure/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Lung/*diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Edema/*diagnostic imaging
MH  - Pulmonary Wedge Pressure
MH  - *Tomography, X-Ray Computed
EDAT- 1984/11/01 00:00
MHDA- 1984/11/01 00:01
CRDT- 1984/11/01 00:00
PHST- 1984/11/01 00:00 [pubmed]
PHST- 1984/11/01 00:01 [medline]
PHST- 1984/11/01 00:00 [entrez]
AID - 10.1536/ihj.25.979 [doi]
PST - ppublish
SO  - Jpn Heart J. 1984 Nov;25(6):979-92. doi: 10.1536/ihj.25.979.