PMID- 6534417
OWN - NLM
STAT- MEDLINE
DCOM- 19850710
LR  - 20061115
IS  - 0006-341X (Print)
IS  - 0006-341X (Linking)
VI  - 40
IP  - 4
DP  - 1984 Dec
TI  - A score test for the possible presence of recessive alleles in generalized 
      ABO-like genetic systems.
PG  - 887-94
AB  - In generalized ABO-like genetic systems, particularly for certain human leukocyte 
      antigen (HLA) loci, it is quite likely, even for large sample sizes, that no 
      double recessives (or 'double blanks') may be found. It has been suggested that 
      all such data should be analyzed as if the true recessive gene frequency were 0. 
      We derive an easily computed score [or C(alpha)] statistic which tests for the 
      possibility that, in such instances, this frequency may exceed 0. An associated 
      point estimator is suggested. The methods are applied to the data analyzed by 
      Smouse and Williams (1982, Biometrics 38, 757-768).
FAU - Gart, J J
AU  - Gart JJ
FAU - Nam, J M
AU  - Nam JM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Biometrics
JT  - Biometrics
JID - 0370625
RN  - 0 (ABO Blood-Group System)
RN  - 0 (HLA Antigens)
SB  - IM
MH  - ABO Blood-Group System/*genetics
MH  - *Alleles
MH  - Biometry
MH  - *Genes, Recessive
MH  - HLA Antigens/*genetics
MH  - Humans
MH  - Models, Genetic
EDAT- 1984/12/01 00:00
MHDA- 1984/12/01 00:01
CRDT- 1984/12/01 00:00
PHST- 1984/12/01 00:00 [pubmed]
PHST- 1984/12/01 00:01 [medline]
PHST- 1984/12/01 00:00 [entrez]
PST - ppublish
SO  - Biometrics. 1984 Dec;40(4):887-94.