PMID- 6538090 OWN - NLM STAT- MEDLINE DCOM- 19840425 LR - 20190908 IS - 0735-7044 (Print) IS - 0735-7044 (Linking) VI - 98 IP - 1 DP - 1984 Feb TI - Dietary self-selection in intact, ovariectomized, and estradiol-treated female rats. PG - 125-37 AB - The effects of estrogenic stimulation on diet selection were examined in intact, estrous cycling rats, ovariectomized (OVX) rats, and OVX rats given estradiol benzoate (EB) hormone replacement therapy. In Experiment 1, OVX was associated with the nearly exclusive choice of the more calorically dense diet of a pair of diets varying in the concentration of one of the three basic macronutrients (i.e., fat, carbohydrate, and protein), an effect that was decreased by EB administration. In the second experiment, dietary self-selection was examined in intact, estrous cycling rats given access to an isocaloric diet triplet of fat, carbohydrate (CHO), and protein. Total caloric intake and body weight did not vary across the estrous cycle. However, diet selection did vary. Fat intake increased; CHO and, to a lesser extent, protein intake decreased during estrus. An opposite diet selection occurred during diestrus. In Experiment 3, OVX resulted in progressive increases in CHO and protein intake, with a concurrent decrease in fat consumption. The EB treatment partially reversed this diet selection profile (Experiment 4). These results were confirmed by diet pairs with both naturally occurring and experimentally produced estrogenic stimulation (Experiments 5 and 6). These data are consistent with the findings of previous research demonstrating estrogenic reduction in CHO intake with standard high-CHO commercial diets. In addition, an increase in fat intake during estrogenic stimulation was found. FAU - Bartness, T J AU - Bartness TJ FAU - Waldbillig, R J AU - Waldbillig RJ LA - eng PT - Journal Article PL - United States TA - Behav Neurosci JT - Behavioral neuroscience JID - 8302411 RN - 4TI98Z838E (Estradiol) SB - IM MH - Animals MH - Body Weight/drug effects MH - Castration MH - Eating/*drug effects MH - Energy Intake/drug effects MH - Estradiol/*pharmacology MH - Estrus/drug effects MH - Female MH - Food Preferences/*drug effects MH - Pregnancy MH - Rats EDAT- 1984/02/01 00:00 MHDA- 1984/02/01 00:01 CRDT- 1984/02/01 00:00 PHST- 1984/02/01 00:00 [pubmed] PHST- 1984/02/01 00:01 [medline] PHST- 1984/02/01 00:00 [entrez] AID - 10.1037//0735-7044.98.1.125 [doi] PST - ppublish SO - Behav Neurosci. 1984 Feb;98(1):125-37. doi: 10.1037//0735-7044.98.1.125.