PMID- 6542490
OWN - NLM
STAT- MEDLINE
DCOM- 19850214
LR  - 20061115
IS  - 0204-3564 (Print)
IS  - 0204-3564 (Linking)
VI  - 6
IP  - 5
DP  - 1984
TI  - [Several peculiarities of hexokinase of malignant and benign tumors in man].
PG  - 42-6
AB  - The total activity and isoenzyme spectrum of hexokinase (HK) were investigated in 
      normal tissues as well as malignant and benign tumours of man. Electrophoresis in 
      agar gel has revealed that the normal tissues are usually characterized by HK-I. 
      In malignant tumours HK-II and additional anode fractions of KH-II and HK-III 
      were observed. The HK isoenzyme spectrum in the benign tumours was similar to 
      those of homologous normal tissues. The values of the HK-II/HK-I ratio were 
      higher in the malignant tumours as compared with the benign tumours and normal 
      tissues. These results may be used for diagnosis. Changes in the isoenzyme 
      spectrum do not depend on histological structure of tumours, are secondary and 
      depend on tumour progression.
FAU - Liubimova, N V
AU  - Liubimova NV
FAU - Gorozhanskaia, E G
AU  - Gorozhanskaia EG
LA  - rus
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
TT  - Nekotorye osobennosti geksokinazy zlokachestvennykh i dobrokachestvennykh 
      opukholei cheloveka.
PL  - Ukraine
TA  - Eksp Onkol
JT  - Eksperimental'naia onkologiia
JID - 8406659
RN  - 0 (Isoenzymes)
RN  - EC 2.7.1.1 (Hexokinase)
SB  - IM
MH  - Breast Neoplasms/enzymology
MH  - Electrophoresis, Agar Gel
MH  - Esophageal Neoplasms/enzymology
MH  - Female
MH  - Hexokinase/*analysis
MH  - Humans
MH  - Isoenzymes/*analysis
MH  - Lung Neoplasms/enzymology
MH  - Neoplasms/*enzymology
MH  - Ovarian Neoplasms/enzymology
MH  - Stomach Neoplasms/enzymology
MH  - Uterine Neoplasms/enzymology
EDAT- 1984/01/01 00:00
MHDA- 1984/01/01 00:01
CRDT- 1984/01/01 00:00
PHST- 1984/01/01 00:00 [pubmed]
PHST- 1984/01/01 00:01 [medline]
PHST- 1984/01/01 00:00 [entrez]
PST - ppublish
SO  - Eksp Onkol. 1984;6(5):42-6.