PMID- 6576185
OWN - NLM
STAT- MEDLINE
DCOM- 19830923
LR  - 20071114
IS  - 0027-8874 (Print)
IS  - 0027-8874 (Linking)
VI  - 71
IP  - 2
DP  - 1983 Aug
TI  - Immune responses of healthy humans 83-104 years of age.
PG  - 265-8
AB  - The immune responses of 19 healthy people 83-104 years of age were compared to 
      those of younger healthy persons. A decline in mitogen response to concanavalin A 
      and pokeweed mitogen, but not to phytohemagglutinin, was observed. Positive skin 
      test to two recall antigens occurred in only 5 of the 19 aged people; 4 of these 
      5 reported a history of blood transfusion. Antibody titers were elevated for 
      persistent DNA viruses but not for RNA viruses. An excess of ABO blood type B was 
      found, but no human leukocyte antigen (HLA)-A or HLA-B type was found in elevated 
      proportion.
FAU - Dworsky, R
AU  - Dworsky R
FAU - Paganini-Hill, A
AU  - Paganini-Hill A
FAU - Arthur, M
AU  - Arthur M
FAU - Parker, J
AU  - Parker J
LA  - eng
GR  - CA-14089/CA/NCI NIH HHS/United States
GR  - CA-24082/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Natl Cancer Inst
JT  - Journal of the National Cancer Institute
JID - 7503089
RN  - 0 (ABO Blood-Group System)
RN  - 0 (Mitogens)
SB  - IM
MH  - ABO Blood-Group System/immunology
MH  - *Aged
MH  - Antibody Formation
MH  - Blood Transfusion
MH  - DNA Viruses/immunology
MH  - Female
MH  - Humans
MH  - *Immunity
MH  - Leukocyte Count
MH  - Lymphocyte Activation
MH  - Male
MH  - Mitogens
MH  - RNA Viruses/immunology
MH  - Skin Tests
EDAT- 1983/08/01 00:00
MHDA- 1983/08/01 00:01
CRDT- 1983/08/01 00:00
PHST- 1983/08/01 00:00 [pubmed]
PHST- 1983/08/01 00:01 [medline]
PHST- 1983/08/01 00:00 [entrez]
PST - ppublish
SO  - J Natl Cancer Inst. 1983 Aug;71(2):265-8.