PMID- 6604162
OWN - NLM
STAT- MEDLINE
DCOM- 19831021
LR  - 20071114
IS  - 0141-2760 (Print)
IS  - 0141-2760 (Linking)
VI  - 11
IP  - 3
DP  - 1983 Jul
TI  - Isolation and quantitation of immune complexes in diabetic syrian hamsters: a 
      chronological study.
PG  - 129-33
AB  - Immune complexes (IC) were isolated from the serum of streptozotocin (Sz)-induced 
      diabetic hamsters by coprecipitation with an equine rheumatoid-C1q factor (RhC). 
      The IC, comprised of an unknown antigen(s) and IgG, occurred at 2 distinct time 
      intervals during the 12-week chronological study. Although all diabetic hamsters 
      with hyperglycemia of 300 mg/dl had IC, there was no correlation between the 
      occurrence or concentration of IC and the degree of hyperglycemia. The cycling 
      nature of IC in the serum of diabetic hamsters suggests that the antigen 
      component either fluctuates chronologically or that the IC contain different 
      antigens that do not occur simultaneously.
FAU - McDonald, T L
AU  - McDonald TL
FAU - Quenette, L
AU  - Quenette L
FAU - Phares, C K
AU  - Phares CK
LA  - eng
GR  - AM 21186/AM/NIADDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Scotland
TA  - J Clin Lab Immunol
JT  - Journal of clinical & laboratory immunology
JID - 7808987
RN  - 0 (Antigen-Antibody Complex)
RN  - 0 (Blood Glucose)
RN  - 0 (Immunoglobulin G)
RN  - 80295-33-6 (Complement C1q)
RN  - EC 3.- (Complement Activating Enzymes)
SB  - IM
MH  - Animals
MH  - Antigen-Antibody Complex/analysis/*isolation & purification
MH  - Blood Glucose/analysis
MH  - Complement Activating Enzymes/metabolism
MH  - Complement C1q
MH  - Cricetinae
MH  - Diabetes Mellitus, Experimental/*immunology
MH  - Immunoelectrophoresis
MH  - Immunoglobulin G/analysis
MH  - Mesocricetus
MH  - Time Factors
EDAT- 1983/07/01 00:00
MHDA- 1983/07/01 00:01
CRDT- 1983/07/01 00:00
PHST- 1983/07/01 00:00 [pubmed]
PHST- 1983/07/01 00:01 [medline]
PHST- 1983/07/01 00:00 [entrez]
PST - ppublish
SO  - J Clin Lab Immunol. 1983 Jul;11(3):129-33.