PMID- 6608870
OWN - NLM
STAT- MEDLINE
DCOM- 19840521
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 53
IP  - 9
DP  - 1984 May 1
TI  - Determination of left ventricular mass by single-photon emission computed 
      tomography with thallium-201.
PG  - 1365-8
AB  - To test the hypothesis that single-photon emission computed tomography (SPECT) 
      might permit accurate, noninvasive measurement of LV mass, SPECT measurements of 
      LV mass to LV weight were compared in 20 mongrel dogs. Projection images of the 
      left ventricle were acquired after intravenous injection of thallium-201 
      (TI-201). Transverse sections were reconstructed using filtered backprojection. 
      Coronal sections were extracted from the reconstructed volume. The boundary of LV 
      uptake of TI-201 in each coronal section was defined automatically using a 
      threshold detector. Scintigraphic LV mass [total number of volume elements 
      (voxels) showing TI-201 uptake X voxel volume X specific gravity of myocardium] 
      was compared to actual LV weight. There was good correlation between 
      scintigraphic LV mass and LV weight. Mean LV weight was 68 +/- 20 g (+/- standard 
      deviation) (range 27 to 94). Mean SPECT LV mass was 66 +/- 19 g (range 28 to 
      100). Linear regression analysis yielded the following relation: SPECT LV mass = 
      0.87 X LV weight + 6.79 (r = 0.91, root-mean-square deviation from regression = 
      7.5). SPECT measurements were reproducible, with a coefficient of variation of 
      0.24%. Thus, SPECT of LV TI-201 distribution can be used to measure LV mass in 
      canine myocardium.
FAU - Wolfe, C L
AU  - Wolfe CL
FAU - Corbett, J R
AU  - Corbett JR
FAU - Lewis, S E
AU  - Lewis SE
FAU - Buja, L M
AU  - Buja LM
FAU - Willerson, J T
AU  - Willerson JT
LA  - eng
GR  - HL 17669/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 0 (Radioisotopes)
RN  - AD84R52XLF (Thallium)
SB  - IM
MH  - Animals
MH  - Dogs
MH  - Heart/anatomy & histology/*diagnostic imaging
MH  - *Radioisotopes
MH  - *Thallium
MH  - *Tomography, Emission-Computed
EDAT- 1984/05/01 00:00
MHDA- 1984/05/01 00:01
CRDT- 1984/05/01 00:00
PHST- 1984/05/01 00:00 [pubmed]
PHST- 1984/05/01 00:01 [medline]
PHST- 1984/05/01 00:00 [entrez]
AID - 0002-9149(84)90095-X [pii]
AID - 10.1016/0002-9149(84)90095-x [doi]
PST - ppublish
SO  - Am J Cardiol. 1984 May 1;53(9):1365-8. doi: 10.1016/0002-9149(84)90095-x.