PMID- 6614150
OWN - NLM
STAT- MEDLINE
DCOM- 19831008
LR  - 20071114
IS  - 0002-9483 (Print)
IS  - 0002-9483 (Linking)
VI  - 61
IP  - 3
DP  - 1983 Jul
TI  - Lack of prominent compensatory polycythemia in traditional native Andeans living 
      at 4,200 meters.
PG  - 355-66
AB  - Red blood cell count (RBC), hemoglobin concentration ([Hb]) and hematocrit (Hct) 
      were measured in 303 male Quechua children and adults, aged 6 to 57 years, living 
      a lifestyle as traditional pastoralists and horticulturalists at a mean altitude 
      of 4,200 m in the Southern Peruvian Andes. Values for RBC, [Hb], and Hct 
      increased with age from middle childhood to young adulthood. However, among 
      adults there was no significant association between age and any of these three 
      parameters. Overall, there was approximately a 10-12% increase in the RBC, [Hb], 
      and Hct above sea-level norms for all age groups. Mean corpuscular volume (MCV) 
      and mean corpuscular hemoglobin (MCH) showed a slight but significant increase 
      with age in children and adolescents, but the mean corpuscular hemoglobin 
      concentration (MCHC) did not. We conclude that the study of highland Quechua 
      Indians, living a traditional lifestyle as pastoralists and horticulturalists, 
      does not support the long-held belief that altitude hypoxia provokes a dramatic 
      compensatory polycythemia in healthy Andeans.
FAU - Garruto, R M
AU  - Garruto RM
FAU - Dutt, J S
AU  - Dutt JS
LA  - eng
GR  - 5 TO1 GMO 1748/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Phys Anthropol
JT  - American journal of physical anthropology
JID - 0400654
RN  - 0 (Hemoglobins)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aging
MH  - *Altitude
MH  - Child
MH  - *Erythrocyte Count
MH  - *Hematocrit
MH  - Hemoglobins/*analysis
MH  - Humans
MH  - Indians, South American
MH  - Male
MH  - Peru
MH  - Polycythemia/*etiology
EDAT- 1983/07/01 00:00
MHDA- 1983/07/01 00:01
CRDT- 1983/07/01 00:00
PHST- 1983/07/01 00:00 [pubmed]
PHST- 1983/07/01 00:01 [medline]
PHST- 1983/07/01 00:00 [entrez]
AID - 10.1002/ajpa.1330610310 [doi]
PST - ppublish
SO  - Am J Phys Anthropol. 1983 Jul;61(3):355-66. doi: 10.1002/ajpa.1330610310.