PMID- 6637782
OWN - NLM
STAT- MEDLINE
DCOM- 19831217
LR  - 20190626
IS  - 0002-8703 (Print)
IS  - 0002-8703 (Linking)
VI  - 106
IP  - 5 Pt 1
DP  - 1983 Nov
TI  - Time to completed redistribution of thallium-201 in exercise myocardial 
      scintigraphy: relationship to the degree of coronary artery stenosis.
PG  - 989-95
AB  - The relationship between the severity of coronary artery stenosis and the time to 
      completed redistribution of thallium 201 (TI-201) defects following maximal 
      exercise was investigated in 59 patients undergoing stress-redistribution TI-201 
      scintigraphy, coronary angiography, and contrast ventriculography. Multiple view 
      TI-201 scintigrams were obtained, beginning 6 minutes (immediately post stress), 
      less than 1 hour (early), 3 to 5 hours (average), and 18 to 24 hours (late) 
      following intravenous TI-201 injection at peak exercise. Angiographic lesions 
      were grouped into five levels of severity by percent stenosis. In the 107 defects 
      which were seen on the immediate post stress images, early redistribution was 
      noted in 15 (14%) and late redistribution was found in 23 (21%). In addition, 
      there was a correlation (r = 0.56) between the time to completed redistribution 
      and the severity of the coronary artery stenosis (p = 0.001). In comparison to 
      defects with early and average redistribution, the segments contralateral to 
      those with defects showing late redistribution more often had a critical stenosis 
      supplying that segment. The frequency of myocardial infarction on ECG and the 
      number of segments with akinetic and dyskinetic wall motion were less in defects 
      undergoing late rather than no redistribution. Thus the time to completed TI-201 
      redistribution following stress appears to be related to the severity of stenosis 
      in the coronary artery supplying the defect. Also, late redistribution is 
      associated with the presence and early redistribution with the absence of a 
      significant stenosis in the coronary artery to the contralateral segment.
FAU - Gutman, J
AU  - Gutman J
FAU - Berman, D S
AU  - Berman DS
FAU - Freeman, M
AU  - Freeman M
FAU - Rozanski, A
AU  - Rozanski A
FAU - Maddahi, J
AU  - Maddahi J
FAU - Waxman, A
AU  - Waxman A
FAU - Swan, H J
AU  - Swan HJ
LA  - eng
GR  - 17651/PHS HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
RN  - 0 (Radioisotopes)
RN  - AD84R52XLF (Thallium)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Arterial Occlusive Diseases/diagnosis/*diagnostic imaging/physiopathology
MH  - Coronary Circulation
MH  - Coronary Disease/diagnosis/*diagnostic imaging/physiopathology
MH  - Electrocardiography
MH  - Exercise Test
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Contraction
MH  - Myocardium/metabolism
MH  - *Radioisotopes
MH  - Radionuclide Imaging
MH  - *Thallium
MH  - Time Factors
EDAT- 1983/11/01 00:00
MHDA- 1983/11/01 00:01
CRDT- 1983/11/01 00:00
PHST- 1983/11/01 00:00 [pubmed]
PHST- 1983/11/01 00:01 [medline]
PHST- 1983/11/01 00:00 [entrez]
AID - 0002-8703(83)90642-7 [pii]
AID - 10.1016/0002-8703(83)90642-7 [doi]
PST - ppublish
SO  - Am Heart J. 1983 Nov;106(5 Pt 1):989-95. doi: 10.1016/0002-8703(83)90642-7.