PMID- 6661301 OWN - NLM STAT- MEDLINE DCOM- 19840319 LR - 20061115 IS - 0037-8771 (Print) IS - 0037-8771 (Linking) VI - 59 IP - 10 DP - 1983 Oct 30 TI - [Transmural distribution of hexokinase, glucose-6-phosphate dehydrogenase and glutamate-oxalacetate transaminase in the left ventricle of the rat]. PG - 1412-5 AB - The changes in hexokinase (HK), glucose-6-phosphate dehydrogenase (G6P-DH) and glutamate aspertate aminotransferase (GOT) activities with the location of tissue within the left ventricle wall have been explored in the rat myocardium. The hearts were cut in 100 micron thick serial sections (see 4) and all sections spectrophotometric procedures (5). No significant transmural gradient in HK activity was observed but the levels of G6P-DH and of GOT activities were significantly higher in the subepicardial tissue and were at their lowest levels in the midmyocardial layers. Our data and previous observations (3,6) indicate that adptions to regional differences in the cardiac work load occurred in the left ventricle wall but that the transmural patterns of enzyme distribution may change with the different animal specie. FAU - Baruffi, F AU - Baruffi F FAU - De Tata, V AU - De Tata V FAU - Gori, Z AU - Gori Z LA - ita PT - English Abstract PT - Journal Article TT - Distribuzione transmurale di esochinasi, glucoso-6-fosfato deidrogenasi e transaminasi glutammico-ossalacetica nel ventricolo sinistro del ratto. PL - Italy TA - Boll Soc Ital Biol Sper JT - Bollettino della Societa italiana di biologia sperimentale JID - 7506962 RN - EC 1.1.1.49 (Glucosephosphate Dehydrogenase) RN - EC 2.6.1.1 (Aspartate Aminotransferases) RN - EC 2.7.1.1 (Hexokinase) SB - IM MH - Animals MH - Aspartate Aminotransferases/*metabolism MH - Female MH - Glucosephosphate Dehydrogenase/*metabolism MH - Heart Ventricles/enzymology MH - Hexokinase/*metabolism MH - Myocardium/*enzymology MH - Rats MH - Rats, Inbred Strains MH - Tissue Distribution EDAT- 1983/10/30 00:00 MHDA- 1983/10/30 00:01 CRDT- 1983/10/30 00:00 PHST- 1983/10/30 00:00 [pubmed] PHST- 1983/10/30 00:01 [medline] PHST- 1983/10/30 00:00 [entrez] PST - ppublish SO - Boll Soc Ital Biol Sper. 1983 Oct 30;59(10):1412-5.