PMID- 6691260
OWN - NLM
STAT- MEDLINE
DCOM- 19840214
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 53
IP  - 1
DP  - 1984 Jan 1
TI  - Influence of length of aortic occlusion with cold potassium cardioplegia on early 
      and late mortality in cardiac valve replacement.
PG  - 182-6
AB  - This study determines if prolonged aortic crossclamp time (ACC) with the use of 
      cold potassium cardioplegia during elective cardiac valve replacement contributed 
      to the risk of operative mortality in 225 patients. In Group I (143 patients), 
      the ACC was less than 120 minutes (mean 86) and in Group II (82 patients), it was 
      greater than 120 minutes (mean 146). The preoperative variables showed that Group 
      II contained more severely ill patients who were undergoing more complex 
      operations than in Group I. The operative mortality rate was 7% in Group I and 
      10% in Group II (p = not significant). Postoperative inotropic support was 
      required in 13% of Group I and 30% of Group II patients (p less than 0.005). 
      Operative mortality in patients in New York Heart Association (NYHA) functional 
      class I and II was 0 and in patients in classes III and IV it was 13% (p less 
      than 0.00008). Five percent of patients in NYHA classes I and II and 32% in 
      classes III and IV required inotropic support (p less than 0.000005). The 
      actuarial survival at 60 months was 88 +/- 3% for Group I and 77 +/- 7% for Group 
      II (NS). For the NYHA class I and II patients, however, it was significantly 
      better (98 +/- 2%) than class III and IV patients (75 +/- 5%) (p less than 
      0.0001). Analysis by logistic equation revealed that the NYHA functional classes 
      III and IV were significant incremental risk factors for probability of 
      in-hospital mortality (p less than 0.0001) but not the ACC time (p greater than 
      0.1).(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Raza, S T
AU  - Raza ST
FAU - Lajos, T Z
AU  - Lajos TZ
FAU - Bhayana, J
AU  - Bhayana J
FAU - Lee, A B Jr
AU  - Lee AB Jr
FAU - Lewin, A N
AU  - Lewin AN
FAU - Gehring, B
AU  - Gehring B
FAU - Puzio, N
AU  - Puzio N
FAU - Schimert, G
AU  - Schimert G
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - RWP5GA015D (Potassium)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aorta
MH  - Cold Temperature
MH  - Constriction
MH  - Female
MH  - Heart Arrest, Induced/*methods
MH  - *Heart Valve Prosthesis
MH  - Heart Valves/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Mortality
MH  - Potassium
MH  - Time Factors
EDAT- 1984/01/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1984/01/01 00:00
PHST- 1984/01/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1984/01/01 00:00 [entrez]
AID - 0002-9149(84)90707-0 [pii]
AID - 10.1016/0002-9149(84)90707-0 [doi]
PST - ppublish
SO  - Am J Cardiol. 1984 Jan 1;53(1):182-6. doi: 10.1016/0002-9149(84)90707-0.