PMID- 6696064
OWN - NLM
STAT- MEDLINE
DCOM- 19840315
LR  - 20171213
IS  - 0002-9513 (Print)
IS  - 0002-9513 (Linking)
VI  - 246
IP  - 1 Pt 1
DP  - 1984 Jan
TI  - Nutritional influences on lipogenesis and thermogenesis after a carbohydrate 
      meal.
PG  - E62-70
AB  - In vivo lipogenesis and thermogenesis were studied for 24 h after ingestion of 
      500 g of carbohydrate (CHO) in subjects who had consumed either a high-fat, a 
      mixed, or a high-CHO diet during the 3-6 days preceding the test. CHO oxidation 
      and conversion to fat was significantly less in the high-fat diet group (222 +/- 
      5 g) than in the mixed (300 +/- 13 g) or high-CHO diet (331 +/- 7 g) groups, 
      resulting in a greater glycogen storage in the high-fat (278 +/- 6 g) than in the 
      other two groups (197 +/- 11 and 170 +/- 2 g). Net lipogenesis occurred sooner 
      and lasted longer in the high-CHO group, amounting to 0.8 +/- 0.5, 3.4 +/- 0.6, 
      and 9 +/- 1 g of lipid synthesized in the high-fat, mixed, and high-CHO groups, 
      respectively. The thermic effect of the CHO load was 5.2 +/- 0.5% on the 
      high-fat, 6.5 +/- 0.4% on the mixed diet, and 8.6 +/- 0.4% on the high-CHO diet. 
      Significant relationships were demonstrated between the postabsorptive nonprotein 
      respiratory quotient and net lipogenesis after the CHO load (r = 0.82) and 
      between net lipogenesis and the increase in energy expenditure (r = 0.71). It is 
      concluded that the antecedent diet influences the amount of net lipogenesis and 
      the magnitude of thermogenesis after a large CHO test meal. However, lipogenesis 
      remains too limited even after such large CHO intakes to cause an increase in the 
      body's fat content.
FAU - Acheson, K J
AU  - Acheson KJ
FAU - Schutz, Y
AU  - Schutz Y
FAU - Bessard, T
AU  - Bessard T
FAU - Ravussin, E
AU  - Ravussin E
FAU - Jequier, E
AU  - Jequier E
FAU - Flatt, J P
AU  - Flatt JP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am J Physiol
JT  - The American journal of physiology
JID - 0370511
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Lipids)
RN  - 0 (Palmitic Acids)
RN  - 2V16EO95H1 (Palmitic Acid)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Adult
MH  - *Body Temperature Regulation
MH  - Calorimetry
MH  - *Dietary Carbohydrates
MH  - Energy Intake
MH  - Energy Metabolism
MH  - Fasting
MH  - Glucose/metabolism
MH  - Humans
MH  - Lipids/*biosynthesis
MH  - Male
MH  - Palmitic Acid
MH  - Palmitic Acids/metabolism
EDAT- 1984/01/01 00:00
MHDA- 1984/01/01 00:01
CRDT- 1984/01/01 00:00
PHST- 1984/01/01 00:00 [pubmed]
PHST- 1984/01/01 00:01 [medline]
PHST- 1984/01/01 00:00 [entrez]
AID - 10.1152/ajpendo.1984.246.1.E62 [doi]
PST - ppublish
SO  - Am J Physiol. 1984 Jan;246(1 Pt 1):E62-70. doi: 10.1152/ajpendo.1984.246.1.E62.