PMID- 6697225
OWN - NLM
STAT- MEDLINE
DCOM- 19840417
LR  - 20190614
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 293
IP  - 2
DP  - 1984 Feb 20
TI  - Dopamine enhances Met-enkephalin efflux from rat striatal slices.
PG  - 364-7
AB  - The basal release of Met-enkephalin immunoreactive material (ME-IR) from rat 
      striatal slices is doubled by the in vitro addition of 5 X 10(-5) M dopamine. The 
      K+ evoked release of ME-IR is also slightly enhanced by exposing the slices to 
      dopamine. The effect of dopamine is shared by apomorphine but not by 
      norepinephrine. Neuroleptics do not alter the basal or the K+-stimulated ME-IR 
      release but reverse the dopamine-induced increase. These results suggest that the 
      stimulation of dopamine receptors may influence the enkephalin release within 
      striatum.
FAU - Pasinetti, G
AU  - Pasinetti G
FAU - Govoni, S
AU  - Govoni S
FAU - di Giovine, S
AU  - di Giovine S
FAU - Spano, P F
AU  - Spano PF
FAU - Trabucchi, M
AU  - Trabucchi M
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
RN  - 58569-55-4 (Enkephalin, Methionine)
RN  - J6292F8L3D (Haloperidol)
RN  - N21FAR7B4S (Apomorphine)
RN  - VTD58H1Z2X (Dopamine)
RN  - X4W3ENH1CV (Norepinephrine)
SB  - IM
MH  - Animals
MH  - Apomorphine/pharmacology
MH  - Corpus Striatum/drug effects/*metabolism
MH  - Dopamine/*pharmacology
MH  - Enkephalin, Methionine/*metabolism
MH  - Haloperidol/administration & dosage
MH  - In Vitro Techniques
MH  - Male
MH  - Norepinephrine/pharmacology
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Stimulation, Chemical
EDAT- 1984/02/20 00:00
MHDA- 1984/02/20 00:01
CRDT- 1984/02/20 00:00
PHST- 1984/02/20 00:00 [pubmed]
PHST- 1984/02/20 00:01 [medline]
PHST- 1984/02/20 00:00 [entrez]
AID - 0006-8993(84)91244-7 [pii]
AID - 10.1016/0006-8993(84)91244-7 [doi]
PST - ppublish
SO  - Brain Res. 1984 Feb 20;293(2):364-7. doi: 10.1016/0006-8993(84)91244-7.