PMID- 6713171 OWN - NLM STAT- MEDLINE DCOM- 19840605 LR - 20190614 IS - 0006-8993 (Print) IS - 0006-8993 (Linking) VI - 295 IP - 1 DP - 1984 Mar 12 TI - Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decarboxylase as a marker. PG - 13-25 AB - The distribution of histidine decarboxylase-like immunoreactivity (HDCI) in the rat central nervous system was studied by the indirect immunofluorescence technique. HDCI cell bodies were concentrated in the posterior hypothalamic area, such as in the tuberal magnocellular nucleus, caudal magnocellular nucleus, posterior hypothalamic nucleus and lateral hypothalamus just lateral to the fasciculus mammillothalamicus at the level of the posterior hypothalamic nucleus. Extensive networks of HDCI fibers of various densities were found in many areas of the brain; they were particularly dense in the hypothalamus but were also found in the following areas: rostrally in the cerebral cortex, olfactory nuclei, medial amygdaloid nucleus, n. tractus diagonalis, and bed nucleus of the stria terminalis, and caudally in the central gray matter of the midbrain and pons, auditory system, n. vestibularis medialis, n. originis nervi facialis, n. parabrachialis, n. commissuralis, n. tractus solitarii, and n. raphe dorsalis. FAU - Watanabe, T AU - Watanabe T FAU - Taguchi, Y AU - Taguchi Y FAU - Shiosaka, S AU - Shiosaka S FAU - Tanaka, J AU - Tanaka J FAU - Kubota, H AU - Kubota H FAU - Terano, Y AU - Terano Y FAU - Tohyama, M AU - Tohyama M FAU - Wada, H AU - Wada H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Netherlands TA - Brain Res JT - Brain research JID - 0045503 RN - 0 (Antigen-Antibody Complex) RN - 0 (Immune Sera) RN - 820484N8I3 (Histamine) RN - EC 4.1.1.- (Carboxy-Lyases) RN - EC 4.1.1.22 (Histidine Decarboxylase) SB - IM MH - Animals MH - Antigen-Antibody Complex MH - Brain/*enzymology MH - Carboxy-Lyases/*metabolism MH - Histamine/*analysis MH - Histidine Decarboxylase/*metabolism MH - Immune Sera MH - Male MH - Neurons/*enzymology MH - Rats MH - Rats, Inbred Strains MH - Tissue Distribution EDAT- 1984/03/12 00:00 MHDA- 1984/03/12 00:01 CRDT- 1984/03/12 00:00 PHST- 1984/03/12 00:00 [pubmed] PHST- 1984/03/12 00:01 [medline] PHST- 1984/03/12 00:00 [entrez] AID - 0006-8993(84)90811-4 [pii] AID - 10.1016/0006-8993(84)90811-4 [doi] PST - ppublish SO - Brain Res. 1984 Mar 12;295(1):13-25. doi: 10.1016/0006-8993(84)90811-4.