PMID- 6740999
OWN - NLM
STAT- MEDLINE
DCOM- 19840807
LR  - 20131121
IS  - 0042-8809 (Print)
IS  - 0042-8809 (Linking)
VI  - 30
IP  - 2
DP  - 1984 Mar-Apr
TI  - [Effect of the intravenous administration of homologous albumin on the lipolytic 
      enzyme activity of rabbit blood plasma].
PG  - 87-91
AB  - Activity of main lipolytic enzymes of rabbit blood plasma, lipoprotein lipase 
      (LPL) and liver tissue triglyceride lipase (L-TGL) as well as intensity of 
      lipoprotein lipolysis in vivo, which was estimated by an increase of unesterified 
      fatty acids in blood plasma, studied after intravenous administration of 
      homologous albumin at a dose of 200 mg/kg of body mass. The data obtained suggest 
      that albumin is involved in regulation of lipoprotein lipolysis due to activation 
      of LPL, caused by asseption of unesterified fatty acids, which are liberated 
      after hydrolysis of triglycerides. This effect was exhibited by albumin only 
      under conditions of active stimulation of lipolytic reactions, it occurs after 
      intravenous administration of heparin (100 IU/kg of body mass). Albumin did not 
      activate lipoprotein lipolysis and lipolytic enzymes in intact animals. Activity 
      of L-TGL in blood plasma was less distinctly subjected to the regulatory effect 
      of albumin.
FAU - Soliternova, I B
AU  - Soliternova IB
FAU - Nikul'cheva, N G
AU  - Nikul'cheva NG
FAU - Sanches Serrano, D
AU  - Sanches Serrano D
LA  - rus
PT  - English Abstract
PT  - Journal Article
TT  - Vliianie vnutrivennogo vvedeniia gomologichnogo al'bumina na aktivnost' 
      lipoliticheskikh fermentov plazmy krovi krolika.
PL  - Russia (Federation)
TA  - Vopr Med Khim
JT  - Voprosy meditsinskoi khimii
JID - 0416601
RN  - 0 (Albumins)
RN  - 0 (Drug Combinations)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Lipoproteins, VLDL)
RN  - 0 (Triglycerides)
RN  - 9005-49-6 (Heparin)
RN  - 97C5T2UQ7J (Cholesterol)
RN  - EC 3.1.1.3 (Lipase)
RN  - EC 3.1.1.34 (Lipoprotein Lipase)
SB  - IM
MH  - Albumins/administration & dosage/*pharmacology
MH  - Animals
MH  - Cholesterol/blood
MH  - Drug Combinations
MH  - Electrophoresis, Polyacrylamide Gel
MH  - Fatty Acids, Nonesterified/*blood
MH  - Heparin/administration & dosage/pharmacology
MH  - Injections, Intravenous
MH  - Lipase/*blood
MH  - Lipoprotein Lipase/*blood
MH  - Lipoproteins, VLDL/blood
MH  - Liver/enzymology
MH  - Male
MH  - Rabbits
MH  - Triglycerides/blood
EDAT- 1984/03/01 00:00
MHDA- 1984/03/01 00:01
CRDT- 1984/03/01 00:00
PHST- 1984/03/01 00:00 [pubmed]
PHST- 1984/03/01 00:01 [medline]
PHST- 1984/03/01 00:00 [entrez]
PST - ppublish
SO  - Vopr Med Khim. 1984 Mar-Apr;30(2):87-91.