PMID- 6752665 OWN - NLM STAT- MEDLINE DCOM- 19821221 LR - 20190821 IS - 0385-5600 (Print) IS - 0385-5600 (Linking) VI - 26 IP - 6 DP - 1982 TI - Appearance of enterotoxigenic Escherichia coli in piglets with diarrhea in connection with feed changes. PG - 467-77 AB - Twelve weaned piglet (3-week-old) were divided into three groups according to time of feed change and observed for diarrhea during the time they were 3 to 8 weeks of age. A total of 553 strains of Escherichia coli were isolated from rectal fecal samples and examined for heat-labile (LT) and heat-stable (ST) enterotoxins, pilus antigens (K88, K99, and 987P), hemolysin (Hly), raffinose utilization (Raf) and drug resistance. Enterotoxins and/or hemolytic E. coli strains appeared in the rectal feces of 5- to 6-week-old piglets with diarrhea in connection with feed change and changing temperatures. Most of the isolates showed multiple drug resistance to sulfonamides (Sa), streptomycin (Sp), ampicillin, and/or mercury. Enterotoxigenic E. coli isolates represented four phenotypes: K88+.LT+.Hly+.Raf+.(SaSmCpTcKmSp) (12 strains), K99+.ST+.Raf+.(TcKm) (7 strains), ST+.Raf+.(TcKm) (7 strains), and ST.+(SaSmKm) (25 strains). The drug resistance determinants were transferable concurrently and some of them mobilized the determinants for K88, LT, Hly, and Raf to an E. coli C strain. FAU - Shimizu, M AU - Shimizu M FAU - Terashima, T AU - Terashima T LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Australia TA - Microbiol Immunol JT - Microbiology and immunology JID - 7703966 SB - IM MH - Animals MH - Diarrhea/microbiology/*veterinary MH - Drug Resistance, Microbial MH - Escherichia coli/genetics/*isolation & purification MH - Feces/microbiology MH - Phenotype MH - Swine/microbiology MH - Swine Diseases/*microbiology EDAT- 1982/01/01 00:00 MHDA- 1982/01/01 00:01 CRDT- 1982/01/01 00:00 PHST- 1982/01/01 00:00 [pubmed] PHST- 1982/01/01 00:01 [medline] PHST- 1982/01/01 00:00 [entrez] AID - 10.1111/j.1348-0421.1982.tb00200.x [doi] PST - ppublish SO - Microbiol Immunol. 1982;26(6):467-77. doi: 10.1111/j.1348-0421.1982.tb00200.x.