PMID- 6762131
OWN - NLM
STAT- MEDLINE
DCOM- 19830407
LR  - 20131121
IS  - 0003-4886 (Print)
IS  - 0003-4886 (Linking)
VI  - 14
IP  - 12
DP  - 1982 Dec
TI  - HLA-A1 and steroid-induced cataracts in renal transplant patients.
PG  - 1116-8
AB  - Posterior subcapsular (PSC) lens changes were found in 32 of 33 steroid-treated 
      renal transplant patients examined with the slit lamp techniques of direct and 
      retroillumination. Only one of 33 age-matched controls had any PSC changes. Six 
      (18%) of the renal transplant patients were bilaterally surgically aphakic 
      because of PSC cataracts that developed while the patient was receiving steroid 
      therapy after transplant surgery. Steroid-induced PSC cataracts were associated 
      with the presence of human leukocyte antigen (HLA) A1, but not with the patient's 
      age, cause of renal failure, total dose of steroids, or duration of steroid 
      therapy.
FAU - Kollarits, C R
AU  - Kollarits CR
FAU - Swann, E R
AU  - Swann ER
FAU - Shapiro, R S
AU  - Shapiro RS
FAU - Gillespie, C M
AU  - Gillespie CM
FAU - Shealy, T A
AU  - Shealy TA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Ann Ophthalmol
JT  - Annals of ophthalmology
JID - 0210137
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-A1 Antigen)
RN  - VB0R961HZT (Prednisone)
RN  - X4W7ZR7023 (Methylprednisolone)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Cataract/*chemically induced/immunology
MH  - Child
MH  - Female
MH  - HLA Antigens/*analysis
MH  - HLA-A1 Antigen
MH  - Humans
MH  - *Kidney Transplantation
MH  - Male
MH  - Methylprednisolone/*adverse effects
MH  - Middle Aged
MH  - Prednisone/*adverse effects
EDAT- 1982/12/01 00:00
MHDA- 1982/12/01 00:01
CRDT- 1982/12/01 00:00
PHST- 1982/12/01 00:00 [pubmed]
PHST- 1982/12/01 00:01 [medline]
PHST- 1982/12/01 00:00 [entrez]
PST - ppublish
SO  - Ann Ophthalmol. 1982 Dec;14(12):1116-8.