PMID- 6769536 OWN - NLM STAT- MEDLINE DCOM- 19800815 LR - 20191210 IS - 0006-8993 (Print) IS - 0006-8993 (Linking) VI - 190 IP - 1 DP - 1980 May 19 TI - Operant control of precentral neurons: control of modal interspike intervals. PG - 29-38 AB - The objects of these experiments were: (a) to determine modal interspike intervals (ISIs) of precentral cells involved in repetitious, gross motor movements; (b) to compare those modal ISIs to the modal ISIs of similar neurons under operant control; and (c) to determine if monkeys could change the modal ISIs of operantly controlled precentral neurons. Data were obtained from 4 monkeys conditioned to produce tonic firing of precentral neurons and one monkey trained to produce repetitious movements of the neck and contralateral limbs. Results are: (a) the modal ISIs from operantly controlled precentral units do not differ significantly from precentral neurons involved in repetitive gross motor movements; and (b) while under operant control, the monkeys cannot modify significantly the modal ISI of the majority of precentral neurons. FAU - Wyler, A R AU - Wyler AR FAU - Lange, S C AU - Lange SC FAU - Neafsey, E J AU - Neafsey EJ FAU - Robbins, C A AU - Robbins CA LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - Netherlands TA - Brain Res JT - Brain research JID - 0045503 SB - IM MH - Animals MH - Conditioning, Operant/*physiology MH - Evoked Potentials MH - Frontal Lobe/*physiology MH - Haplorhini MH - Humans MH - Macaca mulatta MH - Male MH - Movement MH - Neurons/physiology MH - Reinforcement, Psychology MH - Stereotyped Behavior/physiology EDAT- 1980/05/19 00:00 MHDA- 1980/05/19 00:01 CRDT- 1980/05/19 00:00 PHST- 1980/05/19 00:00 [pubmed] PHST- 1980/05/19 00:01 [medline] PHST- 1980/05/19 00:00 [entrez] AID - 0006-8993(80)91157-9 [pii] AID - 10.1016/0006-8993(80)91157-9 [doi] PST - ppublish SO - Brain Res. 1980 May 19;190(1):29-38. doi: 10.1016/0006-8993(80)91157-9.