PMID- 6817239 OWN - NLM STAT- MEDLINE DCOM- 19830214 LR - 20190701 IS - 0304-3940 (Print) IS - 0304-3940 (Linking) VI - 32 IP - 3 DP - 1982 Oct 23 TI - Immunocytology of carbonic anhydrase II in the central nervous system of jimpy mutant mice. PG - 321-7 AB - In agreement with previous observations in rats, carbonic anhydrase II (CAII) demonstrated immunocytochemically with a specific immune serum, is exclusively localized in oligodendrocytes in the central nervous system of both normal and dysmyelinating Jimpy mutant mice. In spite of the lack of myelin, the CAII-containing cells in Jimpy mice are abundant. These data suggest that oligodendrocytes are formed in Jimpy mice but they are not able to reach an advanced stage of maturation as defined by their capacity for producing myelin. FAU - Borrelli, E AU - Borrelli E FAU - Langley, O K AU - Langley OK FAU - Ghandour, M S AU - Ghandour MS FAU - Delaunoy, J P AU - Delaunoy JP FAU - Gombos, G AU - Gombos G LA - eng PT - Journal Article PL - Ireland TA - Neurosci Lett JT - Neuroscience letters JID - 7600130 RN - EC 4.2.1.1 (Carbonic Anhydrases) SB - IM MH - Animals MH - Brain/*enzymology MH - Carbonic Anhydrases/*metabolism MH - Cerebellum/enzymology MH - Cerebral Cortex/enzymology MH - Corpus Callosum/enzymology MH - Female MH - Fluorescent Antibody Technique MH - Hippocampus/enzymology MH - Immunoenzyme Techniques MH - Male MH - Mice MH - Mice, Inbred CBA MH - Mice, Jimpy MH - Myelin Sheath/*enzymology MH - Nerve Fibers, Myelinated/enzymology MH - Oligodendroglia/enzymology EDAT- 1982/10/23 00:00 MHDA- 1982/10/23 00:01 CRDT- 1982/10/23 00:00 PHST- 1982/10/23 00:00 [pubmed] PHST- 1982/10/23 00:01 [medline] PHST- 1982/10/23 00:00 [entrez] AID - 0304-3940(82)90314-7 [pii] AID - 10.1016/0304-3940(82)90314-7 [doi] PST - ppublish SO - Neurosci Lett. 1982 Oct 23;32(3):321-7. doi: 10.1016/0304-3940(82)90314-7.