PMID- 6851263
OWN - NLM
STAT- MEDLINE
DCOM- 19830708
LR  - 20041117
IS  - 0301-0430 (Print)
IS  - 0301-0430 (Linking)
VI  - 19
IP  - 5
DP  - 1983 May
TI  - Red cell survival and red cell enzymes in patients on continuous peritoneal 
      dialysis (CAPD).
PG  - 232-5
AB  - In 11 patients on CAPD with persisting anemia the survival of red cells labelled 
      with 51Cr, red cell mass and the levels of several enzymes within red cells were 
      measured. 51Cr red cell survival was shortened in 9/11 (mean +/- SD:20.0 +/- 4.9 
      days) and correlated with red cell mass, i.e. with the degree of anemia (r = 
      0.79, P less than 0.01). Determinations of the levels of enzymes of the hexose 
      monophosphate shunt and the glycolytic pathway revealed no obvious defects in red 
      cell metabolism. The level of hexokinase (HK) was normal whereas the activities 
      of glucose-6-phosphate dehydrogenase (G-6-PD), 6-phosphogluconate dehydrogenase 
      (6-PGD), glutathione reductase (GR) and pyruvate kinase (PK) as well as reduced 
      glutathione (GSH) were increased significantly. CAPD did not eliminate the 
      hemolytic component of anemia in the majority of these patients.
FAU - Hefti, J E
AU  - Hefti JE
FAU - Blumberg, A
AU  - Blumberg A
FAU - Marti, H R
AU  - Marti HR
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Clin Nephrol
JT  - Clinical nephrology
JID - 0364441
SB  - IM
MH  - Anemia/*metabolism/therapy
MH  - *Erythrocyte Aging
MH  - Erythrocytes/*enzymology
MH  - Female
MH  - Humans
MH  - Kidney Failure, Chronic/therapy
MH  - Male
MH  - Middle Aged
MH  - *Peritoneal Dialysis
MH  - *Peritoneal Dialysis, Continuous Ambulatory
EDAT- 1983/05/01 00:00
MHDA- 1983/05/01 00:01
CRDT- 1983/05/01 00:00
PHST- 1983/05/01 00:00 [pubmed]
PHST- 1983/05/01 00:01 [medline]
PHST- 1983/05/01 00:00 [entrez]
PST - ppublish
SO  - Clin Nephrol. 1983 May;19(5):232-5.