PMID- 685190
OWN - NLM
STAT- MEDLINE
DCOM- 19781025
LR  - 20131121
IS  - 0042-8809 (Print)
IS  - 0042-8809 (Linking)
VI  - 24
IP  - 4
DP  - 1978 Jul-Aug
TI  - [Isoenzyme spectrum and activity of several enzymes of bone marrow erythroid and 
      myeloid cells in rabbits and changes in them under the influence of 
      hydrocortisone].
PG  - 464-9
AB  - Rabbit myeloid myelocaryocytes possessed higher activities of hexokinase (HK) and 
      lactate dehydrogenase (LDH) as compared with those of erythroid cells. The 
      lypolytic activity was twice as high in myeloid myelocaryocytes as in erythroid 
      ones. Both strains of medullar cells did not differ in the activity of 
      glucose-6-phosphate dehydrogenase (G6PD). But the isoenzyme spectra of G6PD 
      varied distinctly in these cells; HK and LDH isoenzyme spectra were the same both 
      in myeloid and erythroid cells. The enzymatic activity was altered dissimilarly 
      in myeloid and erythroid cells after administration of hydrocortisone. In myeloid 
      cells the HK activity was decreased, in the erythroid cells--the HK activity 
      tended to increase and the lipolytic activity was decreased. Alterations in the 
      isoenzyme spectra of G6PD and LDH, caused by hydrocortisone administration, 
      exhibited similar patterns in myeloid and erythroid cells.
FAU - Bel'chenko, D I
AU  - Bel'chenko DI
FAU - Domanskii, V Iu
AU  - Domanskii VIu
FAU - Khanina, N Ia
AU  - Khanina NIa
LA  - rus
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
TT  - Izofermentnyi spektr i aktivnost' nekotorykh fermentov eritroidnykh i mieloidnykh 
      kletok kostnogo mozga krolika i osobennosti ikh izmenenii pod vliianiem 
      gidrokortizona.
PL  - Russia (Federation)
TA  - Vopr Med Khim
JT  - Voprosy meditsinskoi khimii
JID - 0416601
RN  - 0 (Isoenzymes)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 1.1.1.49 (Glucosephosphate Dehydrogenase)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Animals
MH  - Bone Marrow/drug effects/enzymology
MH  - *Bone Marrow Cells
MH  - Chinchilla
MH  - Glucosephosphate Dehydrogenase/metabolism
MH  - Hexokinase/metabolism
MH  - Hydrocortisone/*pharmacology
MH  - *Isoenzymes/metabolism
MH  - L-Lactate Dehydrogenase/metabolism
MH  - Lipid Metabolism
MH  - Rabbits
EDAT- 1978/07/01 00:00
MHDA- 1978/07/01 00:01
CRDT- 1978/07/01 00:00
PHST- 1978/07/01 00:00 [pubmed]
PHST- 1978/07/01 00:01 [medline]
PHST- 1978/07/01 00:00 [entrez]
PST - ppublish
SO  - Vopr Med Khim. 1978 Jul-Aug;24(4):464-9.