PMID- 6869289
OWN - NLM
STAT- MEDLINE
DCOM- 19830826
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 52
IP  - 3
DP  - 1983 Aug
TI  - Abnormal thallium-201 scans in patients with chest pain and angiographically 
      normal coronary arteries.
PG  - 365-70
AB  - We reviewed the exercise thallium-201 (TI-201) scans and clinical data of 41 
      patients with chest pain and normal coronary arteries to identify clinical 
      factors associated with "false-positive" studies. Exercise TI-201 studies were 
      performed before angiography and often precipitated referral. Sex, beta-blocker 
      therapy, anginal pattern, and results of exercise electrocardiography were 
      evaluated and compared with TI-201 imaging. A negative TI-201 study was the most 
      common finding (p less than 0.005). Of the 41 patients, 11 (27%) had abnormal 
      exercise TI-201 scans. No clinical factor was significantly associated with a 
      false-positive TI-201 scans. Of the 11 patients with abnormal scans, 9 had 
      greater than or equal to 1 cardiac abnormality: right bundle branch block in 2, 
      mitral valve prolapse in 3, paroxysmal atrial fibrillation in 2, abnormal left 
      ventricular diastolic pressure in 3, and left bundle branch block in 1. Thus, (1) 
      when results of exercise TI-201 imaging are used to refer patients for 
      angiography, "false-positive" TI-201 studies are common; (2) sex, beta blockade, 
      anginal pattern, and results of exercise electrocardiogram are not useful 
      predictors of a false-positive TI-201 study; and (3) patients with chest pain, 
      normal coronary arteries, and abnormal TI-201 scans frequently have other cardiac 
      abnormalities.
FAU - Berger, B C
AU  - Berger BC
FAU - Abramowitz, R
AU  - Abramowitz R
FAU - Park, C H
AU  - Park CH
FAU - Desai, A G
AU  - Desai AG
FAU - Madsen, M T
AU  - Madsen MT
FAU - Chung, E K
AU  - Chung EK
FAU - Brest, A N
AU  - Brest AN
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 37CB58V15B (thallium chloride)
RN  - AD84R52XLF (Thallium)
SB  - IM
MH  - Coronary Disease/*diagnostic imaging
MH  - False Positive Reactions
MH  - Humans
MH  - Pain/*diagnostic imaging
MH  - Physical Exertion
MH  - Radionuclide Imaging
MH  - *Thallium
MH  - Thorax/*diagnostic imaging
EDAT- 1983/08/01 00:00
MHDA- 1983/08/01 00:01
CRDT- 1983/08/01 00:00
PHST- 1983/08/01 00:00 [pubmed]
PHST- 1983/08/01 00:01 [medline]
PHST- 1983/08/01 00:00 [entrez]
AID - 0002-9149(83)90140-6 [pii]
AID - 10.1016/0002-9149(83)90140-6 [doi]
PST - ppublish
SO  - Am J Cardiol. 1983 Aug;52(3):365-70. doi: 10.1016/0002-9149(83)90140-6.