PMID- 6982691
OWN - NLM
STAT- MEDLINE
DCOM- 19821216
LR  - 20190628
IS  - 0003-4975 (Print)
IS  - 0003-4975 (Linking)
VI  - 34
IP  - 5
DP  - 1982 Nov
TI  - Determinants of operative survival following combined mitral valve replacement 
      and coronary revascularization.
PG  - 482-9
AB  - To determine the operative survival rate following combined mitral valve 
      replacement (MVR) and coronary artery bypass graft (CABG) operation, we evaluated 
      100 patients, who were seen consecutively at the Peter Bent Brigham and Brigham 
      and Women's Hospital from 1972 to 1982. There were 63 men and 37 women; the mean 
      age was 62 years. Thirty-six patients were in New York Heart Association (NYHA) 
      Functional Class III, and 64 were in functional Class IV. Mitral regurgitation 
      was predominant in 76 patients; mitral stenosis, in 24. Emergency operations were 
      performed in 15 patients, and elective or semielective operations were performed 
      in 85. There were 18 operative deaths (18%): 9 in patients having elective 
      operations (10.5%) and 9 in those having emergency operations (60%; p less than 
      0.01). Significant preoperative factors related to operative death were NYHA 
      functional class, increased pulmonary vascular resistance, lower cardiac index, 
      and lower ejection fraction in the nonsurvivors. The rate of survival did not 
      differ according to sex, age, or degree of coronary artery disease. In addition, 
      myocardial protection with potassium cardioplegia and complete coronary 
      revascularization significantly reduced operative mortality in the elective group 
      of patients but did not alter the mortality in the emergency group.
FAU - DiSesa, V J
AU  - DiSesa VJ
FAU - Cohn, L H
AU  - Cohn LH
FAU - Collins, J J Jr
AU  - Collins JJ Jr
FAU - Koster, J K Jr
AU  - Koster JK Jr
FAU - VanDevanter, S
AU  - VanDevanter S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Adult
MH  - Aged
MH  - Coronary Artery Bypass/*mortality
MH  - Coronary Disease/complications
MH  - Female
MH  - Heart Arrest, Induced
MH  - Heart Valve Prosthesis/*mortality
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve
MH  - Mitral Valve Insufficiency/etiology/surgery
MH  - Mitral Valve Prolapse/etiology/surgery
MH  - Rheumatic Heart Disease/complications
EDAT- 1982/11/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1982/11/01 00:00
PHST- 1982/11/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1982/11/01 00:00 [entrez]
AID - S0003-4975(10)62992-X [pii]
AID - 10.1016/s0003-4975(10)62992-x [doi]
PST - ppublish
SO  - Ann Thorac Surg. 1982 Nov;34(5):482-9. doi: 10.1016/s0003-4975(10)62992-x.