PMID- 6986797 OWN - NLM STAT- MEDLINE DCOM- 19800425 LR - 20171213 IS - 0002-9513 (Print) IS - 0002-9513 (Linking) VI - 238 IP - 1 DP - 1980 Jan TI - Alteration of myoelectric activity of small intestine by invasive Escherichia coli. PG - G57-62 AB - Invasive strains of Escherichia coli (4608-58 and TD 213 CL) altered myoelectric activity of the small intestine in New Zealand White rabbits. The altered myoelectric activity had two distinct complex patterns. The first was defined as repetitive bursts of action potentials (RBAPs) that occurred predominantly in infected ligated ileal loops. The RBAP activity is characterized by action potential discharge activity greater than 1.5 s in duration and occurring on three or more successive slow waves on the same electrode recording site. These bursts of action potentials often migrated to adjacent electrode sites. The second complex pattern, defined as the migrating action potential complex (MAPC), occurred predominantly in the uninfected small intestine orad to the ligated ileal loop. The MAPC consists of action potential discharge activity of 2.5 s or longer that propagates aborally over at least two consecutive electrode sites. These studies demonstrated an altered myoelectric pattern, the RBAP, characteristic of invasion within the infected ligated loop. The MAPC, characteristic of noninvasion, was noted in the uninfected proximal small intestine. FAU - Burns, T W AU - Burns TW FAU - Mathias, J R AU - Mathias JR FAU - Martin, J L AU - Martin JL FAU - Carlson, G M AU - Carlson GM FAU - Shields, R P AU - Shields RP LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, Non-P.H.S. PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Am J Physiol JT - The American journal of physiology JID - 0370511 SB - IM MH - Action Potentials MH - Animals MH - Electromyography MH - Escherichia coli Infections/*physiopathology MH - *Gastrointestinal Motility MH - Intestine, Small/*physiopathology MH - Male MH - Rabbits EDAT- 1980/01/01 00:00 MHDA- 1980/01/01 00:01 CRDT- 1980/01/01 00:00 PHST- 1980/01/01 00:00 [pubmed] PHST- 1980/01/01 00:01 [medline] PHST- 1980/01/01 00:00 [entrez] AID - 10.1152/ajpgi.1980.238.1.G57 [doi] PST - ppublish SO - Am J Physiol. 1980 Jan;238(1):G57-62. doi: 10.1152/ajpgi.1980.238.1.G57.