PMID- 7013973
OWN - NLM
STAT- MEDLINE
DCOM- 19810720
LR  - 20190720
IS  - 0304-3835 (Print)
IS  - 0304-3835 (Linking)
VI  - 11
IP  - 1
DP  - 1980 Nov
TI  - 'Non-specific' binding of lac repressor of E. coli to a carcinogen-modified DNA.
PG  - 21-7
AB  - The 'non-specific' binding of lac repressor to a N-hydroxyaminofluorene (N-OH-AF) 
      modified DNA was studied using circular dichroism. The binding process was not 
      altered by the modification of the DNA. A small increase of the binding constant 
      was observed. These results are discussed with respect to the role of carcinogen 
      modification in the protein-nucleic acid recognition phenomena.
FAU - Spodheim-Maurizot, M
AU  - Spodheim-Maurizot M
FAU - Maurizot, J C
AU  - Maurizot JC
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ireland
TA  - Cancer Lett
JT  - Cancer letters
JID - 7600053
RN  - 0 (Carcinogens)
RN  - 0 (DNA, Bacterial)
RN  - 0 (Fluorenes)
RN  - 0 (Hydroxylamines)
RN  - 0 (Repressor Proteins)
RN  - 0 (Transcription Factors)
RN  - 61M94X4V24 (N-hydroxy-2-aminofluorene)
SB  - IM
MH  - Carcinogens/pharmacology
MH  - DNA, Bacterial/*metabolism
MH  - Escherichia coli/*metabolism
MH  - Fluorenes/pharmacology
MH  - Hydroxylamines/pharmacology
MH  - Repressor Proteins/*metabolism
MH  - Transcription Factors/*metabolism
EDAT- 1980/11/01 00:00
MHDA- 1980/11/01 00:01
CRDT- 1980/11/01 00:00
PHST- 1980/11/01 00:00 [pubmed]
PHST- 1980/11/01 00:01 [medline]
PHST- 1980/11/01 00:00 [entrez]
AID - 0304-3835(80)90124-X [pii]
AID - 10.1016/0304-3835(80)90124-x [doi]
PST - ppublish
SO  - Cancer Lett. 1980 Nov;11(1):21-7. doi: 10.1016/0304-3835(80)90124-x.