PMID- 7061262
OWN - NLM
STAT- MEDLINE
DCOM- 19820512
LR  - 20171213
IS  - 0161-7567 (Print)
IS  - 0161-7567 (Linking)
VI  - 52
IP  - 1
DP  - 1982 Jan
TI  - Erythrocyte indices during a competitive marathon.
PG  - 168-72
AB  - Three adult male volunteers ran a competitive marathon (42.2 km) during which 
      there was an average ambient air (dry bulb) temperature of 19.4 degree C, with an 
      average ambient water vapor pressure of 9.5 Toor. Prior to and at 4.8-km (3-mi) 
      intervals throughout the race, venous blood samples were drawn from an indwelling 
      catheter in a peripheral arm vein. In each blood sample the total erythrocyte 
      count (EC) was made, and whole blood hemoglobin concentration, hematocrit, and 
      plasma osmolality were determined. From these measurements, the standard red 
      blood cell (RBC) indices of mean corpuscular volume (MCV), mean corpuscular 
      hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) were 
      calculated. The three subjects completed the race in 191, 240, and 310 min, with 
      weight losses averaging 5.4% of prerace body weight. EC linearly decreased below 
      the prerace control levels of 5.69 X 10(6) RBC/mm3 for the first 14.5 km of the 
      race, so that EC was 4.7% below control levels by this point. Subsequently, EC 
      rose back to control levels by 19.3 km, where it remained for the rest of the 
      race. MCHC, MCH, and calculated total RBC volume did not significantly change 
      during the race. Plasma osmolality related to plasma osmolality. These data 
      indicate the dynamic nature of erythrocyte number and volume during long-duration 
      submaximal exercise, and the extraordinary ability of the human body to maintain 
      RBC indices within narrow limits when confronted with a severe stress such as the 
      marathon.
FAU - Kolka, M A
AU  - Kolka MA
FAU - Stephenson, L A
AU  - Stephenson LA
FAU - Wilkerson, J E
AU  - Wilkerson JE
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Appl Physiol Respir Environ Exerc Physiol
JT  - Journal of applied physiology: respiratory, environmental and exercise physiology
JID - 7801242
SB  - IM
MH  - Adult
MH  - Body Water
MH  - Body Weight
MH  - Erythrocyte Count
MH  - *Erythrocyte Indices
MH  - Humans
MH  - Male
MH  - Osmolar Concentration
MH  - Plasma/physiology
MH  - *Running
EDAT- 1982/01/01 00:00
MHDA- 1982/01/01 00:01
CRDT- 1982/01/01 00:00
PHST- 1982/01/01 00:00 [pubmed]
PHST- 1982/01/01 00:01 [medline]
PHST- 1982/01/01 00:00 [entrez]
AID - 10.1152/jappl.1982.52.1.168 [doi]
PST - ppublish
SO  - J Appl Physiol Respir Environ Exerc Physiol. 1982 Jan;52(1):168-72. doi: 
      10.1152/jappl.1982.52.1.168.