PMID- 7076906
OWN - NLM
STAT- MEDLINE
DCOM- 19820719
LR  - 20190709
IS  - 0190-9622 (Print)
IS  - 0190-9622 (Linking)
VI  - 6
IP  - 4 Pt 1
DP  - 1982 Apr
TI  - Clearing of subacute cutaneous lupus erythematosus around molluscum contagiosum 
      lesions.
PG  - 529-33
AB  - A patient with widespread subacute cutaneous lupus erythematosus (SCLE) developed 
      halos of uninflamed, normal-appearing skin around lesions of molluscum 
      contagiosum. A biopsy confirmed the lack of active lupus erythematosus (LE) in 
      the halo area (neither basal layer liquefaction nor inflammatory infiltrate was 
      present). Direct immunofluorescence of the halo area showed only weak staining 
      with IgG and C3. In contrast, adjacent skin, clinically involved with cutaneous 
      LE, showed both active LE by light microscopy and strong staining with IgG and 
      C3. We feel the molluscum contagiosum lesions that developed in areas of active 
      SCLE somehow suppressed the clinical, histologic, and immunologic expression of 
      SCLE in he surrounding skin. This observation might offer some insight into the 
      poorly understood pathophysiologic mechanisms involved in cutaneous LE.
FAU - Charley, M R
AU  - Charley MR
FAU - Sontheimer, R D
AU  - Sontheimer RD
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Am Acad Dermatol
JT  - Journal of the American Academy of Dermatology
JID - 7907132
RN  - 0 (Complement C3)
RN  - 0 (Immunoglobulins)
SB  - IM
MH  - Adult
MH  - Complement C3/analysis
MH  - Humans
MH  - Immunoglobulins/analysis
MH  - Lupus Erythematosus, Discoid/*complications/immunology/pathology
MH  - Male
MH  - Molluscum Contagiosum/*complications/immunology/pathology
MH  - Skin/immunology/*pathology
EDAT- 1982/04/01 00:00
MHDA- 1982/04/01 00:01
CRDT- 1982/04/01 00:00
PHST- 1982/04/01 00:00 [pubmed]
PHST- 1982/04/01 00:01 [medline]
PHST- 1982/04/01 00:00 [entrez]
AID - S0190-9622(82)70045-3 [pii]
AID - 10.1016/s0190-9622(82)70045-3 [doi]
PST - ppublish
SO  - J Am Acad Dermatol. 1982 Apr;6(4 Pt 1):529-33. doi: 
      10.1016/s0190-9622(82)70045-3.