PMID- 7116591
OWN - NLM
STAT- MEDLINE
DCOM- 19821203
LR  - 20190623
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 66
IP  - 4
DP  - 1982 Oct
TI  - Effect of infarct location on the in-hospital prognosis of patients with first 
      transmural myocardial infarction.
PG  - 742-7
AB  - We studied the in-hospital prognosis of 1105 patients who had their first 
      transmural myocardial infarction; 611 patients (55.3%) had anterior myocardial 
      infarction (AMI) and 494 (44.7%) had inferior myocardial infarction (IMI). 
      Patients with IMI had a significantly lower in-hospital mortality rate (9.1% vs 
      15.6%, p = 0.0014) and significantly lower prevalences of congestive heart 
      failure (39.4% vs 47.6%, p = 0.0066), cardiogenic shock ( 8.7% vs 12.6%, p = 
      0.0384) and conduction defects (left anterior hemiblock, right bundle branch 
      block and intraventricular conduction defect). The patients with AMI had 
      significantly higher peak enzyme levels, and a greater percentage of them (40.1% 
      vs 25.9%) had SGOT greater than 240 IU/l, whereas more patients with IMI (34.6% 
      vs 27.8%) had SGOT less than 120 IU/l (p = 0.0001). When the parallel subgroups 
      were compared according to the peak SGOT levels (less than 120, 120-240, and 
      greater than 240 IU/l, the differences in the mortality and morbidity between the 
      two infarct locations diminished. However, patients with AMI still had a less 
      favorable outcome. Logistic regression analysis demonstrated that both the peak 
      enzyme level and the infarct location had an independent influence on the 
      in-hospital prognosis of patients with first transmural infarction.
FAU - Thanavaro, S
AU  - Thanavaro S
FAU - Kleiger, R E
AU  - Kleiger RE
FAU - Province, M A
AU  - Province MA
FAU - Hubert, J W
AU  - Hubert JW
FAU - Miller, J P
AU  - Miller JP
FAU - Krone, R J
AU  - Krone RJ
FAU - Oliver, G C
AU  - Oliver GC
LA  - eng
GR  - HL-18808/HL/NHLBI NIH HHS/United States
GR  - N01 HV-12481/HV/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.6.1.1 (Aspartate Aminotransferases)
SB  - IM
MH  - Aged
MH  - Aspartate Aminotransferases/blood
MH  - Diabetes Complications
MH  - Electrocardiography
MH  - Female
MH  - Heart Failure/complications
MH  - Humans
MH  - Hypertension/complications
MH  - L-Lactate Dehydrogenase/blood
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/complications/diagnosis/*mortality
MH  - Prognosis
MH  - Shock, Cardiogenic/complications
EDAT- 1982/10/01 00:00
MHDA- 1982/10/01 00:01
CRDT- 1982/10/01 00:00
PHST- 1982/10/01 00:00 [pubmed]
PHST- 1982/10/01 00:01 [medline]
PHST- 1982/10/01 00:00 [entrez]
AID - 10.1161/01.cir.66.4.742 [doi]
PST - ppublish
SO  - Circulation. 1982 Oct;66(4):742-7. doi: 10.1161/01.cir.66.4.742.