PMID- 7118053
OWN - NLM
STAT- MEDLINE
DCOM- 19821202
LR  - 20131121
IS  - 0018-5043 (Print)
IS  - 0018-5043 (Linking)
VI  - 14
IP  - 6
DP  - 1982 Jun
TI  - Mixed meal tolerance test and reactive hypoglycemia.
PG  - 281-3
AB  - Twenty-six patients with symptoms suggestive of postprandial hypoglycemia were 
      investigated by oral glucose tolerance test (OGTT). During the OGTT, symptomatic 
      hypoglycemia occurred in 10 (38.5%). Nine of these 10 sugjects were given mixed 
      meal tolerance tests (MMTT) and symptomatic hypoglycemia failed to occur in any 
      case. During the OGTT the nadir glucose was significantly lower than that during 
      MMTT (44.1 +/- 1.5 vs. 77.3 +/- 4.8 mg/dl +/- SEM, respectively; p less than 
      0.0005). Serum insulin during MMTT peaked significantly earlier than during OGTT 
      (46.7 +/- 7.3 vs. 86.7 +/- 11.7 minutes (SEM, respectively; p less than 0.0125). 
      The early secretion of insulin during MMTT may explain the lack of symptomatic 
      hypoglycemia in these patients. We conclude that reactive hypoglycemia, when 
      tested by a more natural stimulus (such as mixed meal) rather than by OGTT, is 
      uncommon.
FAU - Buss, R W
AU  - Buss RW
FAU - Kansal, P C
AU  - Kansal PC
FAU - Roddam, R F
AU  - Roddam RF
FAU - Pino, J
AU  - Pino J
FAU - Boshell, B R
AU  - Boshell BR
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Horm Metab Res
JT  - Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et 
      metabolisme
JID - 0177722
RN  - 0 (Blood Glucose)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Blood Glucose/analysis
MH  - Female
MH  - *Food
MH  - Glucose Tolerance Test
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Hypoglycemia/*etiology
MH  - Male
MH  - Middle Aged
EDAT- 1982/06/01 00:00
MHDA- 1982/06/01 00:01
CRDT- 1982/06/01 00:00
PHST- 1982/06/01 00:00 [pubmed]
PHST- 1982/06/01 00:01 [medline]
PHST- 1982/06/01 00:00 [entrez]
AID - 10.1055/s-2007-1018995 [doi]
PST - ppublish
SO  - Horm Metab Res. 1982 Jun;14(6):281-3. doi: 10.1055/s-2007-1018995.