PMID- 7121043 OWN - NLM STAT- MEDLINE DCOM- 19821203 LR - 20071114 IS - 0022-5223 (Print) IS - 0022-5223 (Linking) VI - 84 IP - 4 DP - 1982 Oct TI - Determinants of early and late results of repair of atrioventricular septal (canal) defects. PG - 523-42 AB - The anatomic and functional characteristics of 310 consecutive patients undergoing repair of atrioventricular (AV) septal defects were studied. The characteristics of the six leaflets of the common (139 patients) or two-orifice (171 patients) AV valve are described. Interventricular communications were present in 156 patients and major associated cardiac anomalies in 73 (tetralogy of Fallot 20, double-outlet right ventricle nine, and others). Fifty-one patients (16%) died in hospital. The incremental risk of young age disappeared after 1976. Severity of preoperative AV valve incompetence and New York Heart Association (NYHA) functional class affected hospital mortality. Current risks for patients without major associated cardiac anomalies are 0.6% to 4% for patients in NYHA Class III without an interventricular communication, depending on the degree of preoperative AV valve incompetence, and 5% to 13% for such patients with an interventricular communication. Actuarial survival at 12 1/2 years postoperatively is 95% when preoperative AV valve incompetence is absent or mild and 88% when it is more severe (Grade 3, 4, or 5). Actually, 92% of hospital survivors are alive and in NYHA class I or II. Failure of the AV valve repair occurred in 32 (10%) of the 310 patients and occurred more frequently when AV valve incompetence was severe preoperatively. Its frequency is reduced by current repair techniques, except in patients without interventricular communication. FAU - Studer, M AU - Studer M FAU - Blackstone, E H AU - Blackstone EH FAU - Kirklin, J W AU - Kirklin JW FAU - Pacifico, A D AU - Pacifico AD FAU - Soto, B AU - Soto B FAU - Chung, G K AU - Chung GK FAU - Kirklin, J K AU - Kirklin JK FAU - Bargeron, L M Jr AU - Bargeron LM Jr LA - eng GR - HL 11 310/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - J Thorac Cardiovasc Surg JT - The Journal of thoracic and cardiovascular surgery JID - 0376343 SB - IM MH - Age Factors MH - Child, Preschool MH - Endocardial Cushion Defects/complications/diagnosis/*surgery MH - Heart Block/complications MH - Heart Septal Defects/*surgery MH - Humans MH - Infant MH - Methods MH - Mortality EDAT- 1982/10/01 00:00 MHDA- 2001/03/28 10:01 CRDT- 1982/10/01 00:00 PHST- 1982/10/01 00:00 [pubmed] PHST- 2001/03/28 10:01 [medline] PHST- 1982/10/01 00:00 [entrez] PST - ppublish SO - J Thorac Cardiovasc Surg. 1982 Oct;84(4):523-42.