PMID- 7157463 OWN - NLM STAT- MEDLINE DCOM- 19830311 LR - 20190904 IS - 0163-4356 (Print) IS - 0163-4356 (Linking) VI - 4 IP - 4 DP - 1982 TI - A high pressure liquid chromatographic procedure for monitoring 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea levels in body fluids. PG - 389-95 AB - A reverse phase high pressure liquid chromatographic method has been developed for the analysis of 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea (methyl-CCNU) levels present in body fluids. A value obtained for the plasma half-life for a single patient indicates that this may be larger than hitherto expected. FAU - Caddy, B AU - Caddy B FAU - Idowu, O R AU - Idowu OR FAU - Stuart, J F AU - Stuart JF LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Ther Drug Monit JT - Therapeutic drug monitoring JID - 7909660 RN - 0 (Nitrosourea Compounds) RN - 13909-09-6 (Semustine) SB - IM MH - Body Fluids/analysis MH - Chromatography, High Pressure Liquid/methods MH - Humans MH - Nitrosourea Compounds/*analysis MH - Semustine/*analysis/blood/urine EDAT- 1982/01/01 00:00 MHDA- 1982/01/01 00:01 CRDT- 1982/01/01 00:00 PHST- 1982/01/01 00:00 [pubmed] PHST- 1982/01/01 00:01 [medline] PHST- 1982/01/01 00:00 [entrez] AID - 10.1097/00007691-198212000-00010 [doi] PST - ppublish SO - Ther Drug Monit. 1982;4(4):389-95. doi: 10.1097/00007691-198212000-00010.