PMID- 7206769 OWN - NLM STAT- MEDLINE DCOM- 19810528 LR - 20221207 IS - 0022-5223 (Print) IS - 0022-5223 (Linking) VI - 81 IP - 4 DP - 1981 Apr TI - The Bjork-Shiley valve: intermediate-term follow-up. PG - 602-14 AB - We evaluated 643 patients surviving aortic, mitral, and aortic and mitral ("double") valve replacement with the Bjork-Shiley prosthesis from 1 to 72 months (median 38 months) postoperatively. Intermediate-term survival rate was similar to that reported for other prosthetic and bioprosthetic devices. Factors unrelated to the device, but related to preoperative patient characteristics or intraoperative or early postoperative events, had important association with late survival rate. These included previous valve replacement, concomitant ventricular aneurysm resection, black race, preoperative functional class, method of myocardial protection, duration of ischemic arrest, ventricular arrhythmias, and double valve replacement. Concomitant coronary artery bypass grafting and the type of valve lesion had no effect on survival prognosis. Freedom from thromboembolism was equal to or superior to other devices, but valve thrombosis occurred 16 times in 15 patients and caused 13 deaths. Improvement in New York Heart Association (NYHA) functional class occurred in the majority of patients. We conclude that the Bjork-Shiley valve is durable and effective, but, as with other devices, is associated with problems of thromboembolism and thrombosis. Intermediate-term survival is related also to non-device, patient-associated characteristics. FAU - Karp, R B AU - Karp RB FAU - Cyrus, R J AU - Cyrus RJ FAU - Blackstone, E H AU - Blackstone EH FAU - Kirklin, J W AU - Kirklin JW FAU - Kouchoukos, N T AU - Kouchoukos NT FAU - Pacifico, A D AU - Pacifico AD LA - eng GR - HL 13310/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - J Thorac Cardiovasc Surg JT - The Journal of thoracic and cardiovascular surgery JID - 0376343 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Alabama MH - Aortic Valve/*surgery MH - Arrhythmias, Cardiac/complications MH - *Bioprosthesis/adverse effects MH - Black People MH - Child MH - Female MH - Follow-Up Studies MH - Graft Survival MH - Heart Aneurysm/complications MH - *Heart Valve Prosthesis/adverse effects MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve/*surgery MH - Postoperative Complications/diagnosis/*epidemiology MH - Thromboembolism/epidemiology MH - Thrombosis/*epidemiology EDAT- 1981/04/01 00:00 MHDA- 1981/04/01 00:01 CRDT- 1981/04/01 00:00 PHST- 1981/04/01 00:00 [pubmed] PHST- 1981/04/01 00:01 [medline] PHST- 1981/04/01 00:00 [entrez] PST - ppublish SO - J Thorac Cardiovasc Surg. 1981 Apr;81(4):602-14.