PMID- 7267517
OWN - NLM
STAT- MEDLINE
DCOM- 19811029
LR  - 20200303
IS  - 0032-5791 (Print)
IS  - 0032-5791 (Linking)
VI  - 59
IP  - 12
DP  - 1980 Dec
TI  - Strain variation in hematological response of broilers to dietary aflatoxin.
PG  - 2686-91
AB  - The response of clinical blood values to graded levels of dietary aflatoxin was 
      studied in three populations of chickens. Male chicks of two commercial broiler 
      strains, one color-sexed and the other feather-sexed, and a randombred strain 
      were fed dietary aflatoxin at levels of 0, 1.25, 2.50 or 5.0 microgram/g of diet 
      from 1 to 21 days of age. At the conclusion of the 21-day treatment period, all 
      remaining birds were bled by cardiac puncture and packed cell volume (PCV), 
      erythrocyte counts (RBC), hemoglobin concentration (Hb), mean corpuscular volume 
      (MCV), mean corpuscular hemoglobin concentration (MCHC), total plasma protein, 
      and total plasma cholesterol were determined. All strains of broilers were 
      susceptible to aflatoxicosis as detected by total plasma protein and cholesterol. 
      Anemia associated with aflatoxicosis was induced in the two commercial broiler 
      lines, but not in the randombred line. The PCV, RBC, and Hb were diminished from 
      control values in a dose-related fashion by graded levels of aflatoxin in the 
      commercial broilers, but not in the randombred line. Decreases in MCV with no 
      significant changes in MCHC were observed in all strains.
FAU - Lanza, G M
AU  - Lanza GM
FAU - Washburn, K W
AU  - Washburn KW
FAU - Wyatt, R D
AU  - Wyatt RD
LA  - eng
PT  - Journal Article
PL  - England
TA  - Poult Sci
JT  - Poultry science
JID - 0401150
RN  - 0 (Aflatoxins)
RN  - 0 (Blood Proteins)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - IM
MH  - Aflatoxins/*pharmacology
MH  - Anemia/chemically induced/veterinary
MH  - Animals
MH  - Blood Proteins/analysis
MH  - Chickens/*blood
MH  - Cholesterol/blood
MH  - Erythrocyte Count/drug effects
MH  - Erythrocyte Indices/drug effects
MH  - Hemodynamics/drug effects
MH  - Male
MH  - Poultry
MH  - Poultry Diseases/chemically induced
MH  - Species Specificity
EDAT- 1980/12/01 00:00
MHDA- 1980/12/01 00:01
CRDT- 1980/12/01 00:00
PHST- 1980/12/01 00:00 [pubmed]
PHST- 1980/12/01 00:01 [medline]
PHST- 1980/12/01 00:00 [entrez]
AID - S0032-5791(19)34951-X [pii]
AID - 10.3382/ps.0592686 [doi]
PST - ppublish
SO  - Poult Sci. 1980 Dec;59(12):2686-91. doi: 10.3382/ps.0592686.