PMID- 72788
OWN - NLM
STAT- MEDLINE
DCOM- 19780127
LR  - 20190827
IS  - 0340-5354 (Print)
IS  - 0340-5354 (Linking)
VI  - 216
IP  - 1
DP  - 1977 Aug 18
TI  - Combined application of cytodiagnostic technics to the cerebrospinal fluid.
PG  - 1-8
AB  - The major purpose of the examination of the cells in the cerebrospinal fluid 
      (CSF) is the diagnosis of malignant growths. However, unequivocal tumor cell 
      diagnosis is often problematical, since cells of local origin can also 
      demonstrate considerable proliferative activity and great morphological variety. 
      In these circumstances, it is advisable to evaluate cells from several points of 
      view. One can demonstrate morphological characteristics with panoptic staining 
      and can gain an impression of the RNA content of a cell with acridine orange (AO) 
      fluorescent stain. Quantitative measurements of DNA synthesis in vitro can be 
      made by labelling with tritiated thymidine. Multidimensional cytodiagnosis gives 
      a comprehensive impression of the quality of the cells in question and provides 
      the clinician with information which can be valuable for subsequent diagnostic 
      and therapeutic efforts.
FAU - Kolmel, H W
AU  - Kolmel HW
FAU - Chone, B K
AU  - Chone BK
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - J Neurol
JT  - Journal of neurology
JID - 0423161
RN  - VC2W18DGKR (Thymidine)
SB  - IM
MH  - Adenocarcinoma/cerebrospinal fluid
MH  - Adolescent
MH  - Aged
MH  - Autoradiography
MH  - Brain Neoplasms/cerebrospinal fluid
MH  - Breast Neoplasms/cerebrospinal fluid
MH  - Central Nervous System Diseases/*cerebrospinal fluid
MH  - Cytodiagnosis/methods
MH  - Female
MH  - Histocytochemistry/methods
MH  - Humans
MH  - Middle Aged
MH  - Staining and Labeling
MH  - Stomach Neoplasms/cerebrospinal fluid
MH  - Thymidine/metabolism
EDAT- 1977/08/18 00:00
MHDA- 1977/08/18 00:01
CRDT- 1977/08/18 00:00
PHST- 1977/08/18 00:00 [pubmed]
PHST- 1977/08/18 00:01 [medline]
PHST- 1977/08/18 00:00 [entrez]
AID - 10.1007/BF00312809 [doi]
PST - ppublish
SO  - J Neurol. 1977 Aug 18;216(1):1-8. doi: 10.1007/BF00312809.