PMID- 7304208 OWN - NLM STAT- MEDLINE DCOM- 19820120 LR - 20081121 IS - 0001-6772 (Print) IS - 0001-6772 (Linking) VI - 111 IP - 4 DP - 1981 Apr TI - Lactate concentrations after short, maximal exercise at various glycogen levels. PG - 465-9 AB - The present study was designed to evaluate the effects of changes in glycogen concentrations on lactate accumulation in human skeletal muscle during a 1 min maximal muscle fatigue test (MFT). All subjects first performed the MFT during a control experiment. Four subjects then performed the MFT again 1 h after prolonged exercise. Seven other subjects performed the MFT again after a 3 day carbohydrate (CHO) poor diet and again after 4 additional days of a CHO rich diet. The m. vastus lateralis was biopsied prior to (for glycogen determinations) and immediately after (for lactate determinations) each performance of the MFT. High but similar lactate concentrations were observed (22.3 mmol x kg-1 w.w.) with normal and supernormal glycogen levels. Lactate was significantly reduced following both the prolonged exercise (to 7.0 mmol x kg-1 w.w.) and the CHO poor diet (to 16.8 mmol x kg-1 w.w.). Alterations in muscle strength and fatigue patterns were also observed from the dietary manipulations but they were neither commensurate with the changes in metabolite concentrations nor statistically significant. FAU - Jacobs, I AU - Jacobs I LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Acta Physiol Scand JT - Acta physiologica Scandinavica JID - 0370362 RN - 0 (Dietary Carbohydrates) RN - 0 (Lactates) RN - 9005-79-2 (Glycogen) SB - IM MH - Adult MH - Dietary Carbohydrates/administration & dosage MH - Glycogen/*metabolism MH - Humans MH - Lactates/*metabolism MH - Male MH - Muscle Contraction MH - Muscles/*metabolism MH - *Physical Exertion OID - NASA: 82064819 EDAT- 1981/04/01 00:00 MHDA- 1981/04/01 00:01 CRDT- 1981/04/01 00:00 PHST- 1981/04/01 00:00 [pubmed] PHST- 1981/04/01 00:01 [medline] PHST- 1981/04/01 00:00 [entrez] AID - 10.1111/j.1748-1716.1981.tb06764.x [doi] PST - ppublish SO - Acta Physiol Scand. 1981 Apr;111(4):465-9. doi: 10.1111/j.1748-1716.1981.tb06764.x.