PMID- 7305520
OWN - NLM
STAT- MEDLINE
DCOM- 19820120
LR  - 20190628
IS  - 0003-4975 (Print)
IS  - 0003-4975 (Linking)
VI  - 32
IP  - 4
DP  - 1981 Oct
TI  - Early operative intervention in aortic bacterial endocarditis.
PG  - 347-50
AB  - Since 1974, 14 patients have required valve replacement for native aortic valve 
      bacterial endocarditis at Vanderbilt University Medical Center. There were 7 male 
      and 7 female patients ranging from 11 to 65 years old. Nine of the patients were 
      less than 27 years old. All patients had congestive heart failure as a 
      complication of the bacterial endocarditis and were in New York Heart Association 
      (NYHA) Functional Class III or IV. Two patients were seen initially with 
      arrhythmias, 3 had episodes of septic emboli, and 1 patient was operated on 
      immediately after sustaining a cardiac arrest. Echocardiogram was utilized in 9 
      patients, and cardiac catheterization was performed in 6 patients who were 
      suspected to have concomitant mitral valve or coronary artery disease. All 
      patients were operated on within two weeks after the institution of antibiotic 
      therapy, and there were no operative or early postoperatively deaths. 
      Preoperative blood cultures were positive in 13 patients, with streptococcus 
      cultured in 6 patients and staphylococcus in 4. Escherichia coli and enterococcus 
      were the other pathogens cultured. All patients received antibiotics 
      intravenously for a total of six weeks. There has been 1 late postoperative 
      death, which occurred 2 months following operation in a patient with myocardial 
      failure unresponsive to treatment. Two patients underwent reoperation, 1 because 
      of a persistent aorto-right ventricular fistula and the second because of 
      paraprosthetic aortic regurgitation. Nine patients are now in NYHA Functional 
      Class I and 4 are in Class II.
FAU - Prager, R L
AU  - Prager RL
FAU - Maples, M D
AU  - Maples MD
FAU - Hammon, J W Jr
AU  - Hammon JW Jr
FAU - Friesinger, G C
AU  - Friesinger GC
FAU - Bender, H W Jr
AU  - Bender HW Jr
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Anti-Bacterial Agents/therapeutic use
MH  - *Aortic Valve
MH  - Child
MH  - Endocarditis, Bacterial/drug therapy/etiology/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Staphylococcal Infections/surgery
MH  - Streptococcal Infections/surgery
MH  - Time Factors
EDAT- 1981/10/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1981/10/01 00:00
PHST- 1981/10/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1981/10/01 00:00 [entrez]
AID - S0003-4975(10)61755-9 [pii]
AID - 10.1016/s0003-4975(10)61755-9 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 1981 Oct;32(4):347-50. doi: 10.1016/s0003-4975(10)61755-9.