PMID- 730856
OWN - NLM
STAT- MEDLINE
DCOM- 19790324
LR  - 20191210
IS  - 0021-9940 (Print)
IS  - 0021-9940 (Linking)
VI  - 92
IP  - 5
DP  - 1978 Oct
TI  - Habituation of the EEG arousal response in rats: short- and long-term effects, 
      frequency specificity, and wake--sleep transfer.
PG  - 803-14
AB  - Presentation of auditory stimuli over interstimulus intervals (ISIs) of several 
      minutes to sleeping rats produced significant habituation of the 
      electroencephalographic (EEG) arousal response. The arousal response habituated 
      to an asymptote after only two or three stimulus presentations. Little or no 
      spontaneous recovery occurred between sessions separated by 24 or 72 hr. The 
      habituation produced by a single stimulus presentation was retained for at least 
      24 hr, and orderly habituation was shown with a 24-hr ISI. Approximately 90% 
      retention of habituation was shown 32 days following 10 stimulus presentations, 
      and some degree of retention was shown for as long as 50 days. After habituation 
      had reached a long-term asymptote, 600 stimulus presentations over 2-sec ISIs 
      produced further response decrements, but these decrements recovered completely 
      within a matter of minutes and responsiveness returned to the previously 
      established long-term asymptote. Habituation was shown to be frequency-specific 
      over both 24-hr and 32-day intervals. Habituation produced by stimulus 
      presentations to awake animals transferred to the condition in which stimuli were 
      presented to sleeping animals.
FAU - Leaton, R N
AU  - Leaton RN
FAU - Jordan, W P
AU  - Jordan WP
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Comp Physiol Psychol
JT  - Journal of comparative and physiological psychology
JID - 0414612
SB  - IM
MH  - Acoustic Stimulation
MH  - Animals
MH  - Arousal/*physiology
MH  - Brain/*physiology
MH  - Electroencephalography
MH  - Habituation, Psychophysiologic/*physiology
MH  - Male
MH  - Rats
MH  - Retention, Psychology
MH  - Sleep/*physiology
MH  - Time Factors
MH  - Transfer, Psychology
MH  - Wakefulness/*physiology
EDAT- 1978/10/01 00:00
MHDA- 1978/10/01 00:01
CRDT- 1978/10/01 00:00
PHST- 1978/10/01 00:00 [pubmed]
PHST- 1978/10/01 00:01 [medline]
PHST- 1978/10/01 00:00 [entrez]
AID - 10.1037/h0077538 [doi]
PST - ppublish
SO  - J Comp Physiol Psychol. 1978 Oct;92(5):803-14. doi: 10.1037/h0077538.