PMID- 7347823
OWN - NLM
STAT- MEDLINE
DCOM- 19821218
LR  - 20091111
IS  - 0033-4979 (Print)
IS  - 0033-4979 (Linking)
VI  - 17
IP  - 4
DP  - 1981 Dec
TI  - [Hexokinase activity of erythrocytes in cancer patients].
PG  - 431-7
AB  - In the present work we have considered the following erythrocyte enzymatic 
      activities; hexokinase (HK), pyruvate kinase (PK), 
      glucose-6-phosphate-dehydrogenase (G6PD), 6-phosphogluconate-dehydrogenase 
      (6PGD), glicero phosphate-isomerase (PHI) and glutathione-reductase (GR) in the 
      red blood cells of 130 subjects of which 55 were healthy or with non cancerous 
      pathology and 75 with malignant tumors. Evident modification has been shown only 
      for the HK which together with fructose-6-phosphate-kinase (PFK) and PK are 
      limiting steps of glycolysis. The increased HK activity value resulted 
      particularly significant in red blood cells of patients affected by well 
      differentiated adenocarcinoma.
FAU - Sensini, A
AU  - Sensini A
FAU - Braussi, M
AU  - Braussi M
FAU - Spadoni, M
AU  - Spadoni M
FAU - Giacchi, R
AU  - Giacchi R
LA  - ita
PT  - English Abstract
PT  - Journal Article
TT  - Attivita esocinasica negli eritrociti di soggetti neoplastici.
PL  - Italy
TA  - Quad Sclavo Diagn
JT  - Quaderni Sclavo di diagnostica clinica e di laboratorio
JID - 0040616
RN  - EC 1.1.1.43 (Phosphogluconate Dehydrogenase)
RN  - EC 1.1.1.49 (Glucosephosphate Dehydrogenase)
RN  - EC 1.8.1.7 (Glutathione Reductase)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 2.7.1.40 (Pyruvate Kinase)
RN  - EC 5.3.1.9 (Glucose-6-Phosphate Isomerase)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Erythrocytes/*enzymology
MH  - Female
MH  - Glucose-6-Phosphate Isomerase/blood
MH  - Glucosephosphate Dehydrogenase/blood
MH  - Glutathione Reductase/blood
MH  - Hexokinase/*blood
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neoplasms/blood/*enzymology
MH  - Phosphogluconate Dehydrogenase/blood
MH  - Pyruvate Kinase/blood
EDAT- 1981/12/01 00:00
MHDA- 1981/12/01 00:01
CRDT- 1981/12/01 00:00
PHST- 1981/12/01 00:00 [pubmed]
PHST- 1981/12/01 00:01 [medline]
PHST- 1981/12/01 00:00 [entrez]
PST - ppublish
SO  - Quad Sclavo Diagn. 1981 Dec;17(4):431-7.