PMID- 7397969
OWN - NLM
STAT- MEDLINE
DCOM- 19801021
LR  - 20190623
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 62
IP  - 2
DP  - 1980 Aug
TI  - QRS mapping in the evaluation of acute anterior myocardial infarction.
PG  - 266-76
AB  - In 42 patients with acute anterior myocardial infarction (AMI), we studied the 
      course of Q-wave development and R-wave reduction during the first 48 hours after 
      the onset of chest pain. We used precordial mapping in relation to clinical 
      features, hemodynamic measurements and enzyme release. Q waves developed within 
      6-14 hours (mean 9 hours) after onset of symptoms. R-wave amplitudes demonstrated 
      nearly a reflected image: They reduced abruptly 5-11 hours (mean 9 hours) after 
      onset of chest pain, coinciding with ST-segment elevation. In 14 patients (group 
      A, 33%) after initial QRS alterations, there were no further changes. Twenty 
      patients (group B, 48%) had a distinct new increase of Q waves (delta sigma Q = 
      3.0 +/- 2.0 mV/hours) and further R-wave reduction (-delta sigma R = 1.0 +/- 0.6 
      mV/hour) simultaneous with new severe chest pain and a delayed second increase of 
      enzyme release corresponding with extension of infarction. There were no 
      significant differences between the groups in age, hemodynamics and infarct size 
      calculated from creatine kinase release. Eight patients (group C, 19%) had 
      contradictory findings. Our findings are consistent with previous results 
      indicating that the critical period for intervention is very small except in 
      patients with extension of necrosis.
FAU - von Essen, R
AU  - von Essen R
FAU - Merx, W
AU  - Merx W
FAU - Doerr, R
AU  - Doerr R
FAU - Effert, S
AU  - Effert S
FAU - Silny, J
AU  - Silny J
FAU - Rau, G
AU  - Rau G
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
RN  - 0 (Isoenzymes)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bundle-Branch Block/physiopathology
MH  - Creatine Kinase/blood
MH  - *Electrocardiography
MH  - Female
MH  - Humans
MH  - Isoenzymes
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis
MH  - Pain/physiopathology
MH  - Pericarditis/diagnosis
MH  - Thorax
MH  - Time Factors
EDAT- 1980/08/01 00:00
MHDA- 1980/08/01 00:01
CRDT- 1980/08/01 00:00
PHST- 1980/08/01 00:00 [pubmed]
PHST- 1980/08/01 00:01 [medline]
PHST- 1980/08/01 00:00 [entrez]
AID - 10.1161/01.cir.62.2.266 [doi]
PST - ppublish
SO  - Circulation. 1980 Aug;62(2):266-76. doi: 10.1161/01.cir.62.2.266.