PMID- 7425996 OWN - NLM STAT- MEDLINE DCOM- 19801216 LR - 20191210 IS - 0001-8244 (Print) IS - 0001-8244 (Linking) VI - 10 IP - 1 DP - 1980 Jan TI - Language and cognitive development in 47,XXX females followed since birth. PG - 31-41 AB - In this report, data are presented on language and cognitive development in an unselected group of eleven 47,XXX females, followed since birth, who are now 6--14 years old. The results of the Yale Developmental Exam (at 2 years) and the Illinois Test of Psycholinguistic Abilities (ITPA) (at 4--6 years) show an early delay in language development. Those girls who presently have serious language and learning problems were significantly delayed in first walking or talking, whereas the relatively unaffected girls were not. Results of the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) at 4 years of age and the Wechsler Intelligence Scale for Children (WISC or WISC-R) at 8 years of age are similar and show a generalized depression of both verbal and nonverbal abilities. Thus, unlike 45,X females or 47,XXX males, triple-X females do not have a specifically nonverbal or verbal cognitive deficit. FAU - Pennington, B AU - Pennington B FAU - Puck, M AU - Puck M FAU - Robinson, A AU - Robinson A LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Behav Genet JT - Behavior genetics JID - 0251711 SB - IM MH - Adolescent MH - Child MH - Child, Preschool MH - Female MH - Humans MH - Intelligence MH - Intelligence Tests MH - *Language Development MH - Language Development Disorders/genetics MH - Learning Disabilities/*genetics MH - *Sex Chromosomes MH - *Trisomy MH - *X Chromosome EDAT- 1980/01/01 00:00 MHDA- 1980/01/01 00:01 CRDT- 1980/01/01 00:00 PHST- 1980/01/01 00:00 [pubmed] PHST- 1980/01/01 00:01 [medline] PHST- 1980/01/01 00:00 [entrez] AID - 10.1007/BF01067317 [doi] PST - ppublish SO - Behav Genet. 1980 Jan;10(1):31-41. doi: 10.1007/BF01067317.