PMID- 7449076
OWN - NLM
STAT- MEDLINE
DCOM- 19810324
LR  - 20191023
IS  - 0009-9090 (Print)
IS  - 0009-9090 (Linking)
VI  - 10
IP  - 4
DP  - 1980 Jul
TI  - Serum total IgE in normal subjects and the influence of a family history of 
      allergy.
PG  - 423-31
AB  - The purpose of this study was to establish the range of serum total 
      immunoglobulin E (IgE) in a healthy population free of personal and family 
      history of allergy, and to determine whether a family history of allergy 
      influenced serum IgE levels. Using commercially available Phadebas reagents, the 
      mean serum IgE in eighty-four adults aged 17-30 years with no personal or family 
      history of allergy was found to be 38.8 iu/ml. Seventy-five percent of subjects 
      had a serum IgE below 50 iu/ml and in only one subject was serum IgE in excess of 
      150 iu/ml, which we suggest be taken as the upper limit of normal. When healthy 
      subjects with no personal history but with a family history of allergy were 
      included with this normal population, the mean serum IgE in 207 subjects was 95.4 
      iu/ml and the upper limit of the distribution curve over 200 iu/ml, suggesting an 
      influence of genetic factors on IgE production.
FAU - Sears, M R
AU  - Sears MR
FAU - Chow, C M
AU  - Chow CM
FAU - Morseth, D J
AU  - Morseth DJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Clin Allergy
JT  - Clinical allergy
JID - 0311172
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Asthma/genetics/immunology
MH  - Eczema/genetics/immunology
MH  - Female
MH  - Humans
MH  - Hypersensitivity/*genetics/immunology
MH  - *Immunoglobulin E
MH  - Male
MH  - Migraine Disorders/genetics/immunology
MH  - Rhinitis, Allergic, Seasonal/genetics/immunology
EDAT- 1980/07/01 00:00
MHDA- 1980/07/01 00:01
CRDT- 1980/07/01 00:00
PHST- 1980/07/01 00:00 [pubmed]
PHST- 1980/07/01 00:01 [medline]
PHST- 1980/07/01 00:00 [entrez]
AID - 10.1111/j.1365-2222.1980.tb02125.x [doi]
PST - ppublish
SO  - Clin Allergy. 1980 Jul;10(4):423-31. doi: 10.1111/j.1365-2222.1980.tb02125.x.